Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.37 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.37 |
| ▸ | ASPH | Q12797 | 1/20 | 0.37 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.37 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.37 |
| ▸ | HIF1AN | Q9NWT6 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | PREP | P48147 | 1/20 | 0.36 |
| ▸ | FAP | Q12884 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13006890 | 0.84 | ITGB3 (0.48) | HSD17B10SMN1; SMN2ITGB3ITGA2B | |
| SCHEMBL13006886 | 0.81 | GAA (0.49) | HSD17B10KDM4EHTTALDH1A1 | |
| SCHEMBL13621109 | 0.81 | ITGB3 (0.43) | HSD17B10SMN1; SMN2KDM4EHTTALDH1A1 | |
| SCHEMBL13006883 | 0.80 | KDM4E (0.51) | HSD17B10SMN1; SMN2KDM4EHTTALDH1A1 | |
| SCHEMBL1653856 | 0.78 | KMT2A (0.50) | HSD17B10SMN1; SMN2ALDH1A1ITGB3ITGA2B | |
| SCHEMBL8016072 | 0.77 | RXFP1 (0.43) | HSD17B10SMN1; SMN2HTTALDH1A1LMNA | |
| SCHEMBL13006872 | 0.77 | KDM4E (0.46) | HSD17B10SMN1; SMN2KDM4EHTTALDH1A1 | |
| SCHEMBL12139854 | 0.76 | HSD17B10 (0.49) | HSD17B10SMN1; SMN2LMNANPSR1HSD11B1 | |
| SCHEMBL21569640 | 0.76 | HSD17B10 (0.54) | HSD17B10SMN1; SMN2KDM4EALDH1A1NPSR1 | |
| SCHEMBL13006880 | 0.76 | NPSR1 (0.67) | ALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100310535-A1 | METHOD FOR EXPANDING HEMATOPOIETIC STEM CELLS USING HETEROCYCLIC COMPOUND | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2010-12-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100310535-A1 | METHOD FOR EXPANDING HEMATOPOIETIC STEM CELLS USING HETEROCYCLIC COMPOUND | HCLS1, CD44, NES | HSD17B10 1336/4885SMN1; SMN2 457/4885KDM4E 2378/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.