Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10413660 | 0.95 | TSHR (0.49) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL221578 | 0.90 | TSHR (0.50) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL15276 | 0.89 | TSHR (0.55) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL5446210 | 0.89 | TSHR (0.55) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL676406 | 0.88 | TSHR (0.47) | TSHRTHRBPOLBAPEX1HTT | |
| Hydrogen Sulfide SCHEMBL329768 | 0.87 | TSHR (0.53) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL29962797 | 0.87 | TSHR (0.53) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL17201482 | 0.87 | TSHR (0.53) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL23437 | 0.87 | TSHR (0.53) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL29961454 | 0.87 | TSHR (0.53) | TSHRTHRBPOLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7851547-B2 | Curable composition and coated article | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2010-12-14 | — | — | US | disclosed |
| US-20070212557-A1 | Curable composition and coated article | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2007-09-13 | — | — | US | disclosed |