Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17229936 | 0.98 | TSHR (0.46) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL21373908 | 0.96 | TSHR (0.44) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL14280528 | 0.95 | TSHR (0.46) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL26363956 | 0.94 | TSHR (0.43) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL14571766 | 0.94 | TSHR (0.43) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL17229939 | 0.94 | TSHR (0.49) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL17229941 | 0.93 | TSHR (0.51) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL17229940 | 0.89 | THRB (0.46) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL15276 | 0.89 | TSHR (0.55) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL5446210 | 0.89 | TSHR (0.55) | TSHRTHRBPOLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8258248-B2 | Preparation of cationic terpolymers and personal care compositions comprising said terpolymers | BASF SE (DE) | 2012-09-04 | — | — | US | disclosed |
| US-8187581-B2 | Copolymers from acryloyldimethyltaurine or an acryloyldimethyltaurate, olefinically unsaturated, noncationic, crosslinking comonomer, olefinically unsaturated, cationic comonomer having oxygen, nitrogen, sulfur or phosphorus, silicon-containing component, macromonomer having oxygen, nitrogen, sulfur | CLARIANT PRODUKTE (DEUTSCHLAND) GMBH (DE) | 2012-05-29 | — | — | US | disclosed |
| US-8062630-B2 | Polymer from acryloyldimethyltaurine, olefinically unsaturated, cationic comonomer, unsaturated, noncationic, crosslinking comonomer, an unsaturated silicon containing comonomer, a crosslinking macromonomer; a thickener, bodying agent, emulsifier, dispersant and/or stabilizer | CLARIANT PRODUKTE (DEUTSCHLAND) GMBH (DE) | 2011-11-22 | — | — | US | disclosed |
| US-20110257016-A1 | Gel Formulations that are Stable for Storage, Comprising at Least Two Substantially Unmixed Hydrogels | BASF SE (DE) | 2011-10-20 | — | — | US | disclosed |
| US-7943157-B2 | copolymer based on acryloxydimethyltaurine; water soluble, water swelling | CLARIANT PRODUKTE (DEUTSCHLAND) GMBH (DE) | 2011-05-17 | — | — | US | disclosed |
| US-7566763-B2 | Stable dispersion concentrates | CLARIANT PRODUKTE (DEUTSCHLAND) GMBH (DE) | 2009-07-28 | — | — | US | disclosed |
| US-20090175804-A1 | Preparation of cationic terpolymers and personal care compositions comprising said terpolymers | BASF SE (DE) | 2009-07-09 | — | — | US | disclosed |
| US-20080207773-A1 | Cosmetic, pharmaceutical and dermatological products | CLARIANT GMBH (DE) | 2008-08-28 | — | — | US | disclosed |
| US-7399478-B2 | Cosmetic, pharmaceutical and dermatological products | CLARIANT PRODUKTE (DEUTSCHLAND) GMBH (DE) | 2008-07-15 | — | — | US | disclosed |
| US-7393520-B2 | Decorative cosmetic and dermatological products | CLARIANT PRODUKTE (DEUTSCHLAND) GMBH (DE) | 2008-07-01 | — | — | US | disclosed |
| US-20080107617-A1 | Surfactant-containing cosmetic, dermatological and pharmaceutical agents | CLARIANT PRODUKTE (DEUTSCHLAND) GMBH | 2008-05-08 | — | — | US | disclosed |
| US-20080069793-A1 | Surfactant-free cosmetic, dermatological and pharmaceutical agents | CLARIANT PRODUKTE (DEUTSCHLAND) GMBH | 2008-03-20 | — | — | US | disclosed |
| US-7332155-B2 | Surfactant-containing cosmetic, dermatological and pharmaceutical agents | CLARIANT PRODUKTE (DEUTSCHLAND) GMBH (DE) | 2008-02-19 | — | — | US | disclosed |
| US-7300914-B2 | Process for the preparation of stable polymer concentrates | CLARIANT PRODUKTE (DEUTSCHLAND) GMBH (DE) | 2007-11-27 | — | — | US | disclosed |
| US-7297328-B2 | Surfactant-free cosmetic, dermatological and pharmaceutical agents | CLARIANT PRODUKTE (DEUTSCHLAND) GMBH (DE) | 2007-11-20 | — | — | US | disclosed |
| US-7244421-B2 | Cosmetic and dermatological hair-treatment agents | CLARIANT PRODUKTE (DEUTSCHLAND) GMBH (DE) | 2007-07-17 | — | — | US | disclosed |
| US-7241853-B2 | Printing processes employing intermediate transfer with molten intermediate transfer materials | XEROX CORPORATION (US) | 2007-07-10 | — | — | US | disclosed |
| US-7186774-B2 | Silicone-modified comb polymers based on acryloyldimethyltaurine acid (2-acrylamido-2-methyl-1-propanesulfonic acid) | CLARIANT PRODUKTE (DEUTSCHLAND) GMBH (DE) | 2007-03-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090175804-A1 | Preparation of cationic terpolymers and personal care compositions comprising said terpolymers | CUTA, TERB1, PARG | TSHR 2225/4885THRB 2302/4885POLB 455/4885 |
| US-20110257016-A1 | Gel Formulations that are Stable for Storage, Comprising at Least Two Substantially Unmixed Hydrogels | HSP90AA1, HSP90B1, HSPA1B | TSHR 4485/4885THRB 4426/4885POLB 3213/4885 |
| US-20080069793-A1 | Surfactant-free cosmetic, dermatological and pharmaceutical agents | FFAR3, FFAR1, FFAR2 | TSHR 2759/4885THRB 4436/4885POLB 533/4885 |
| US-20080107617-A1 | Surfactant-containing cosmetic, dermatological and pharmaceutical agents | SGMS1, SUCLG1, SGMS2 | TSHR 3075/4885THRB 4608/4885POLB 406/4885 |
| US-20080207773-A1 | Cosmetic, pharmaceutical and dermatological products | TPMT, FFAR3, MTHFD2 | TSHR 2975/4885THRB 4490/4885POLB 665/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.