Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 13/20 | 0.50 |
| ▸ | HTR7 | P34969 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | CNR1 | P21554 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13354921 | 0.81 | CNR2 (0.53) | CNR2HTR7TSHRCNR1LMNA | |
| SCHEMBL7057530 | 0.79 | CNR2 (0.52) | CNR2HTR7TSHRCNR1LMNA | |
| SCHEMBL14261229 | 0.79 | CNR2 (0.51) | CNR2TSHRCNR1MAPT | |
| SCHEMBL7057627 | 0.76 | CNR2 (0.49) | CNR2HTR7TSHRCNR1 | |
| SCHEMBL13322667 | 0.76 | CNR2 (0.54) | CNR2HTR7CNR1LMNA | |
| SCHEMBL7059035 | 0.76 | CNR2 (0.47) | CNR2HTR7TSHRCNR1LMNA | |
| SCHEMBL7059044 | 0.76 | CNR2 (0.47) | CNR2HTR7TSHRCNR1LMNA | |
| SCHEMBL14261219 | 0.75 | CNR2 (0.64) | CNR2HTR7TSHRCNR1LMNA | |
| SCHEMBL13007482 | 0.74 | CNR2 (0.50) | CNR2CNR1 | |
| SCHEMBL10704403 | 0.73 | ABCB1 (0.60) | CNR2TSHRCNR1POLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1861377-B1 | BENZIMIDAZOLONE DERIVATIVES AS CB2 RECEPTOR LIGANDS | PFIZER (US) | 2010-12-29 | — | — | EP | disclosed |