Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 7/20 | 0.50 |
| ▸ | CNR1 | P21554 | 3/20 | 0.50 |
| ▸ | HTR4 | Q13639 | 7/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13007407 | 0.74 | CNR2 (0.50) | CNR2CNR1 | |
| SCHEMBL739903 | 0.72 | MEN1 (0.50) | CNR2CNR1 | |
| SCHEMBL738526 | 0.68 | CNR2 (1.00) | CNR2CNR1HTR4 | |
| SCHEMBL20768925 | 0.64 | CNR2 (0.37) | CNR2CNR1HTR4APEX1 | |
| SCHEMBL20769119 | 0.64 | CNR2 (0.39) | CNR2CNR1HTR4APEX1 | |
| SCHEMBL739683 | 0.62 | HTR7 (0.49) | CNR2 | |
| SCHEMBL24200345 | 0.62 | CYP1A2 (0.50) | — | |
| SCHEMBL14261089 | 0.61 | GAA (0.37) | CNR2APEX1 | |
| SCHEMBL8406860 | 0.58 | OPRL1 (0.51) | — | |
| SCHEMBL8293251 | 0.58 | POLB (0.40) | CNR2CNR1HTR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1861377-B1 | BENZIMIDAZOLONE DERIVATIVES AS CB2 RECEPTOR LIGANDS | PFIZER (US) | 2010-12-29 | — | — | EP | disclosed |