Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHMT2 | P34897 | 1/20 | 0.41 |
| ▸ | TACR3 | P29371 | 2/20 | 0.41 |
| ▸ | TACR1 | P25103 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | APAF1 | O14727 | 1/20 | 0.39 |
| ▸ | NSD2 | O96028 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | BCL3 | P20749 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13007442 | 0.75 | CNR2 (0.44) | SHMT2TACR3LMNAMALT1POLB | |
| SCHEMBL13007444 | 0.75 | CNR2 (0.46) | SHMT2TACR3TACR1LMNAMALT1 | |
| SCHEMBL13007102 | 0.75 | CNR2 (0.54) | SHMT2TACR3TACR1LMNAMALT1 | |
| SCHEMBL13007330 | 0.75 | SHMT2 (0.45) | SHMT2TACR3LMNAMALT1KMT2A | |
| SCHEMBL14260931 | 0.74 | CNR2 (0.56) | SHMT2TACR3TACR1LMNAKMT2A | |
| SCHEMBL738519 | 0.73 | CNR2 (0.65) | CNR2 | |
| SCHEMBL14261344 | 0.73 | POLB (0.46) | SHMT2TACR3TACR1LMNAMALT1 | |
| SCHEMBL13007374 | 0.73 | CNR2 (0.55) | SHMT2TACR3TACR1LMNAMALT1 | |
| SCHEMBL13007414 | 0.73 | SHMT2 (0.45) | SHMT2TACR3LMNAMALT1KMT2A | |
| SCHEMBL13007109 | 0.72 | CNR2 (0.43) | SHMT2TACR3TACR1LMNAMALT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1861377-B1 | BENZIMIDAZOLONE DERIVATIVES AS CB2 RECEPTOR LIGANDS | PFIZER (US) | 2010-12-29 | — | — | EP | disclosed |