SCHEMBL13008486

SCHEMBL13008486

C=CNC(=O)Nc1ccc(-c2nc(-c3ccccc3)c(-c3ccccc3)[nH]2)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.54
KDM4E B2RXH2 4/20 0.54
ALDH1A1 P00352 3/20 0.54
GLA P06280 3/20 0.54
GAA P10253 3/20 0.54
HPGD P15428 3/20 0.54
MEN1 O00255 3/20 0.52
MAPK13 O15264 5/20 0.51
MAPK12 P53778 5/20 0.51
MAPK11 Q15759 5/20 0.51
MAPK14 Q16539 5/20 0.51
GCGR P47871 2/20 0.51
NOX1 Q9Y5S8 1/20 0.51
RAF1 P04049 4/20 0.50
HPSE Q9Y251 1/20 0.50
MAPT P10636 2/20 0.49
CYP1A2 P05177 1/20 0.49
CYP2C19 P33261 1/20 0.49
GFER P55789 1/20 0.49
TP53 P04637 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4551617 0.81 KDM4E (0.67) KMT2AKDM4EALDH1A1GLAGAA
SCHEMBL13008490 0.80 KMT2A (0.59) KMT2AKDM4EALDH1A1GLAGAA
SCHEMBL13008480 0.80 KMT2A (0.62) KMT2AKDM4EALDH1A1GLAGAA
SCHEMBL14355066 0.79 RAF1 (0.62) KMT2AKDM4EALDH1A1GLAGAA
SCHEMBL6466096 0.76 RAF1 (0.68) KMT2AKDM4EALDH1A1GLAGAA
SCHEMBL5074753 0.76 MAPK13 (0.83) KMT2AKDM4EALDH1A1GLAGAA
SCHEMBL29622965 0.75 KDM4E (0.58) KMT2AKDM4EALDH1A1GLAGAA
Hydrochloric Acid SCHEMBL29623104 0.74 KDM4E (0.57) KMT2AKDM4EALDH1A1GLAGAA
SCHEMBL16667652 0.74 MAPK13 (0.83) KMT2AKDM4EALDH1A1GLAGAA
SCHEMBL104130 0.74 MAPK13 (0.82) KMT2AKDM4EALDH1A1GLAGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8304157-B2 Toner and manufacturing method thereof KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2012-11-06 US disclosed
US-8304157-B2 Toner and manufacturing method thereof KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2012-11-06 US disclosed
US-20100323290-A1 TONER AND MANUFACTURING METHOD THEREOF KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2010-12-23 US disclosed
US-20100323290-A1 TONER AND MANUFACTURING METHOD THEREOF KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2010-12-23 US disclosed