SCHEMBL13008683

SCHEMBL13008683

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nearest known ligand 0.46

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ SERPINC1 P01008 4/20 0.46
▸ F10 P00742 6/20 0.46
▸ BDNF P23560 3/20 0.37
▸ PTN P21246 2/20 0.37
▸ MDK P21741 2/20 0.37
▸ FGF1 P05230 3/20 0.36
▸ FGF2 P09038 1/20 0.36
▸ F2 P00734 2/20 0.36
▸ CXCL10 P02778 1/20 0.33
▸ CXCL8 P10145 1/20 0.33
▸ CCL2 P13500 1/20 0.33
▸ CCL5 P13501 1/20 0.33
▸ CXCL12 P48061 1/20 0.33
▸ HPSE Q9Y251 3/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13008574 1.00 SERPINC1 (0.46) SERPINC1F10BDNFPTNMDK
SCHEMBL13008687 0.95 SERPINC1 (0.48) SERPINC1F10BDNFPTNMDK
SCHEMBL13008576 0.91 SERPINC1 (0.44) SERPINC1F10BDNFPTNMDK
SCHEMBL13431400 0.79 MDK (0.55) SERPINC1F10BDNFPTNMDK
SCHEMBL12920566 0.77 SERPINC1 (0.51) SERPINC1F10FGF1FGF2HPSE
SCHEMBL13765947 0.75 F10 (0.51) SERPINC1F10BDNFPTNMDK
SCHEMBL13039102 0.74 SERPINC1 (0.57) SERPINC1F10BDNFPTNMDK
SCHEMBL14363911 0.74 SERPINC1 (0.57) SERPINC1F10BDNFPTNMDK
SCHEMBL12606391 0.74 SERPINC1 (0.58) SERPINC1F10BDNFPTNMDK
SCHEMBL13039108 0.74 SERPINC1 (0.54) SERPINC1F10FGF1FGF2F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100317846-A1 Production Of L-Iduronate Containing Polysaccharides THE UNIVERSITY OF MANCHESTER (GB) 2010-12-16 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100317846-A1 Production Of L-Iduronate Containing Polysaccharides IDUA, IDO1, IDO2 SERPINC1 1729/4885F10 122/4885BDNF 3686/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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