SCHEMBL1300913

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL22208862	0.89	LCK (0.61)	HSD17B2DPP4CA12CA1CA2
	SCHEMBL27455432	0.85	HSD17B2 (0.59)	HSD17B2DPP4CA12CA1CA2
	SCHEMBL22208578	0.85	CA12 (0.54)	CA12CA1CA2CA7CA9
	SCHEMBL6859316	0.84	KMT2A (0.54)	HSD17B2DPP4LCKFYNLMNA
	SCHEMBL13468453	0.84	HSD17B2 (0.62)	HSD17B2DPP4CA12CA1CA2
	SCHEMBL24379203	0.83	LCK (0.53)	CA12CA1CA2CA7CA9
	SCHEMBL1301113	0.83	LCK (0.48)	HSD17B2DPP4CA12CA1CA2
	SCHEMBL13469249	0.83	HSD17B2 (0.56)	HSD17B2DPP4CA12CA1CA2
	SCHEMBL12109024	0.82	CA12 (0.51)	CA12CA1CA2CA7CA9
	SCHEMBL28097982	0.81	HSD17B2 (0.55)	HSD17B2DPP4CA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.