SCHEMBL13009135

SCHEMBL13009135

CN1c2ccccc2N(c2ccc3c(-c4cc5ccccc5c5ccccc45)c4cc(N5c6ccccc6N(C)c6ccccc65)ccc4c(-c4ccc5ccccc5c4)c3c2)c2ccccc21

nearest known ligand 0.40

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
AKT1 P31749 1/20 0.40
GPR84 Q9NQS5 1/20 0.34
MET P08581 1/20 0.32
CYP11B1 P15538 1/20 0.32
HSP90AA1 P07900 1/20 0.31
SOS1 Q07889 1/20 0.30
ALOX5 P09917 1/20 0.30
GSTP1 P09211 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13008764 0.94 AKT1 (0.40) AKT1GPR84METCYP11B1HSP90AA1
SCHEMBL13008378 0.91 AKT1 (0.44) AKT1METCYP11B1HSP90AA1ALOX5
SCHEMBL13427524 0.91 CYP11B1 (0.34) AKT1CYP11B1SOS1
SCHEMBL13427604 0.90 AKT1 (0.41) AKT1GPR84METHSP90AA1GSTP1
SCHEMBL13008367 0.89 AKT1 (0.43) AKT1METHSP90AA1SOS1
SCHEMBL13427598 0.89 AKT1 (0.40) AKT1GPR84METHSP90AA1SOS1
SCHEMBL13427595 0.88 AKT1 (0.44) AKT1GPR84METHSP90AA1SOS1
SCHEMBL13427570 0.88 AKT1 (0.42) AKT1METCYP11B1HSP90AA1GSTP1
SCHEMBL13427597 0.87 AKT1 (0.41) AKT1METCYP11B1HSP90AA1ALOX5
SCHEMBL13427565 0.87 AKT1 (0.41) AKT1METCYP11B1HSP90AA1ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2256176-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same Gracel Display Inc. (KR) 2010-12-01 EP disclosed
US-20100051106-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2010-03-04 US disclosed
US-20100051106-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2010-03-04 US disclosed
EP-2141214-A2 Novel organic electroluminescent compounds and organic electroluminescent device using the same Gracel Display Inc. (KR) 2010-01-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100051106-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same RPL36, RPL39, RPL36A AKT1 3459/4885GPR84 1648/4885MET 3253/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.