Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE2 | O96020 | 2/20 | 0.54 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.54 |
| ▸ | CDK2 | P24941 | 2/20 | 0.54 |
| ▸ | CDK4 | P11802 | 1/20 | 0.54 |
| ▸ | CCND1 | P24385 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | APAF1 | O14727 | 1/20 | 0.44 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.44 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.43 |
| ▸ | AKT2 | P31751 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29404936 | 0.95 | CDK2 (0.49) | CCNE2CCNE1CDK2CDK4CCND1 | |
| SCHEMBL25296388 | 0.95 | CDK2 (0.49) | CCNE2CCNE1CDK2CDK4CCND1 | |
| SCHEMBL9673690 | 0.80 | CCNE2 (0.58) | CCNE2CCNE1CDK2CDK4CCND1 | |
| SCHEMBL6749017 | 0.79 | CDK4 (0.52) | CCNE2CCNE1CDK2CDK4CCND1 | |
| SCHEMBL9672281 | 0.78 | MEN1 (0.50) | PAX8TDP1CDC25BBLMMEN1 | |
| SCHEMBL7090159 | 0.75 | CDK4 (0.71) | CCNE2CCNE1CDK2CDK4CCND1 | |
| SCHEMBL6749016 | 0.73 | CDK4 (0.58) | CCNE2CCNE1CDK2CDK4CCND1 | |
| SCHEMBL4025522 | 0.72 | CCNE2 (0.71) | CCNE2CCNE1CDK2CDK4CCND1 | |
| SCHEMBL7148608 | 0.71 | CDK4 (0.66) | CCNE2CCNE1CDK2CDK4CCND1 | |
| SCHEMBL21970645 | 0.71 | MAOB (0.65) | RAB9APOLBAPAF1MAOBCASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1292573-B1 | SUBSTITUTED THIOACETAMIDES | CEPHALON INC (US) | 2010-12-29 | — | — | EP | disclosed |