⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13329991 | 0.87 | TYMP (0.32) | — | |
| SCHEMBL12765859 | 0.87 | TYMP (0.32) | — | |
| SCHEMBL13374809 | 0.87 | TYMP (0.32) | — | |
| SCHEMBL24829632 | 0.87 | TYMP (0.32) | — | |
| SCHEMBL25747161 | 0.87 | TYMP (0.32) | — | |
| SCHEMBL14064222 | 0.86 | TYMP (0.31) | — | |
| SCHEMBL14005196 | 0.85 | TYMP (0.31) | — | |
| SCHEMBL30205820 | 0.82 | — | — | |
| SCHEMBL6854140 | 0.82 | SLC6A1 (0.33) | — | |
| SCHEMBL26270123 | 0.82 | SLC6A1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100317714-A1 | COMPLEX MOLECULE INTERFERING THE EXPRESSION OF TARGET GENES AND ITS PREPARING METHODS | SUZHOU RIBO LIFE SCIENCE CO., LTD (CN) | 2010-12-16 | — | — | US | disclosed |
| US-20100317714-A1 | COMPLEX MOLECULE INTERFERING THE EXPRESSION OF TARGET GENES AND ITS PREPARING METHODS | SUZHOU RIBO LIFE SCIENCE CO., LTD (CN) | 2010-12-16 | — | — | US | disclosed |