Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR2 | P50052 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3065488 | 0.90 | S1PR1 (0.36) | AGTR2 | |
| SCHEMBL3066084 | 0.83 | LYN (0.35) | AGTR2 | |
| SCHEMBL3069896 | 0.77 | LYN (0.37) | AGTR2 | |
| SCHEMBL13010641 | 0.76 | AGTR2 (0.37) | AGTR2 | |
| SCHEMBL3049357 | 0.75 | LYN (0.36) | AGTR2 | |
| SCHEMBL3055160 | 0.75 | S1PR1 (0.38) | AGTR2 | |
| SCHEMBL3070006 | 0.74 | S1PR1 (0.38) | — | |
| SCHEMBL3069777 | 0.74 | AGTR2 (0.39) | AGTR2 | |
| SCHEMBL3063261 | 0.74 | AGTR2 (0.35) | AGTR2 | |
| SCHEMBL3054836 | 0.74 | AGTR2 (0.34) | AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1368342-B3 | BENZIMIDAZOLE AND PYRIDYLIMIDAZOLE DERIVATIVES AS LIGANDS FOR GABA RECEPTORS | NEUROGEN CORP (US) | 2010-12-01 | — | — | EP | disclosed |