Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | XDH | P47989 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MITF | O75030 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2950922 | 0.90 | NPC1 (0.55) | NPC1RAB9AMAPTTP53LMNA | |
| SCHEMBL10263221 | 0.83 | NPC1 (0.47) | NPC1RAB9AMAPTTP53LMNA | |
| SCHEMBL2252001 | 0.81 | NPC1 (0.60) | NPC1RAB9AMAPTTP53LMNA | |
| SCHEMBL2252159 | 0.79 | NPC1 (0.58) | NPC1RAB9AMAPTTP53LMNA | |
| SCHEMBL12311647 | 0.79 | NPC1 (0.58) | NPC1RAB9AMAPTTP53LMNA | |
| SCHEMBL13010482 | 0.79 | NPC1 (0.50) | NPC1RAB9AMAPTTP53LMNA | |
| SCHEMBL6680571 | 0.78 | NPC1 (0.72) | NPC1RAB9AMAPTTP53LMNA | |
| SCHEMBL20100122 | 0.77 | NPC1 (0.60) | NPC1RAB9AMAPTTP53LMNA | |
| SCHEMBL19901704 | 0.77 | NPC1 (0.60) | NPC1RAB9AMAPTTP53LMNA | |
| SCHEMBL27283831 | 0.77 | NPC1 (0.60) | NPC1RAB9AMAPTTP53LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100327738-A1 | POLYMER COMPOUND AND ORGANIC ELECTROLUMINESCENCE ELEMENT USING THE SAME | SHOWA DENKO K.K. (JP) | 2010-12-30 | — | — | US | disclosed |
| US-20100327738-A1 | POLYMER COMPOUND AND ORGANIC ELECTROLUMINESCENCE ELEMENT USING THE SAME | SHOWA DENKO K.K. (JP) | 2010-12-30 | — | — | US | disclosed |