Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.47 |
| ▸ | RAB9A | P51151 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | XDH | P47989 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2950922 | 0.89 | NPC1 (0.55) | NPC1RAB9AMAPTTP53LMNA | |
| SCHEMBL13010504 | 0.83 | NPC1 (0.49) | NPC1RAB9AMAPTTP53LMNA | |
| SCHEMBL10262795 | 0.82 | NPC1 (0.41) | NPC1RAB9AMAPTTP53LMNA | |
| SCHEMBL2252001 | 0.79 | NPC1 (0.60) | NPC1RAB9AMAPTTP53LMNA | |
| SCHEMBL12600290 | 0.79 | NPC1 (0.60) | NPC1RAB9AMAPTTP53LMNA | |
| SCHEMBL10263403 | 0.79 | NR1H4 (0.45) | NPC1RAB9AMAPTTP53LMNA | |
| SCHEMBL19486779 | 0.79 | NR1H4 (0.45) | NPC1RAB9AMAPTTP53LMNA | |
| SCHEMBL10263009 | 0.78 | L3MBTL1 (0.44) | NPC1RAB9AMAPTTP53LMNA | |
| SCHEMBL2252159 | 0.78 | NPC1 (0.58) | NPC1RAB9AMAPTTP53LMNA | |
| SCHEMBL12311647 | 0.78 | NPC1 (0.58) | NPC1RAB9AMAPTTP53LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2468731-A1 | CYCLIC AZINE DERIVATIVES, PROCESSES FOR PRODUCING THESE, AND ORGANIC ELECTROLUMINESCENT ELEMENT CONTAINING THESE AS COMPONENT | Tosoh Corporation (JP) | 2012-06-27 | — | — | EP | disclosed |