Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.51 |
| ▸ | GFER | P55789 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | AURKA | O14965 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29394920 | 0.88 | KDM4E (0.60) | MEN1KMT2AMAPK10GFERKDM4E | |
| SCHEMBL1496803 | 0.81 | CXCR2 (0.50) | CXCR2MEN1KMT2AKDM4EPOLB | |
| SCHEMBL2343124 | 0.80 | ALDH1A1 (0.62) | CXCR2MEN1KMT2AKDM4EHTT | |
| SCHEMBL2443393 | 0.80 | CXCR2 (0.49) | CXCR2MEN1KMT2AKDM4EPOLB | |
| SCHEMBL9409090 | 0.80 | JAK2 (0.56) | MEN1KMT2AMAPK10GFERKDM4E | |
| SCHEMBL1610470 | 0.79 | CXCR2 (0.48) | CXCR2KMT2AKDM4EPOLBATM | |
| SCHEMBL1548893 | 0.77 | DHODH (0.55) | CXCR2MEN1KMT2AKDM4EPOLB | |
| SCHEMBL1612628 | 0.77 | CXCR2 (0.46) | CXCR2KMT2AKDM4EPOLBATM | |
| SCHEMBL13010894 | 0.76 | ALDH1A1 (0.45) | MEN1KMT2AMAPK10GFERKDM4E | |
| SCHEMBL27999264 | 0.76 | KMT2A (0.66) | MEN1KMT2AMAPK10GFERKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2264031-A2 | A NOVEL BENZOXAZINE BENZIMIDAZOLE DERIVATIVE, A PHARMACEUTICAL COMPOSITION COMPRISING THE SAME, AND A USE THEREOF | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 2010-12-22 | — | — | EP | disclosed |