Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK9 | P50750 | 16/20 | 0.49 |
| ▸ | CCNT1 | O60563 | 15/20 | 0.49 |
| ▸ | IKBKB | O14920 | 3/20 | 0.46 |
| ▸ | CHUK | O15111 | 3/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CSF1R | P07333 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 2/20 | 0.45 |
| ▸ | CASP7 | P55210 | 2/20 | 0.45 |
| ▸ | CDK1 | P06493 | 1/20 | 0.45 |
| ▸ | CDK2 | P24941 | 1/20 | 0.45 |
| ▸ | GSK3B | P49841 | 1/20 | 0.45 |
| ▸ | CDK7 | P50613 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21620887 | 0.91 | CDK9 (0.60) | CDK9CCNT1CASP3CASP7CDK1 | |
| SCHEMBL21620453 | 0.85 | CCNT1 (0.57) | CDK9CCNT1 | |
| SCHEMBL30380981 | 0.80 | CDK9 (0.52) | CDK9CCNT1IKBKBCHUKCYP2C9 | |
| SCHEMBL3411433 | 0.80 | CDK9 (0.52) | CDK9CCNT1IKBKBCHUKCYP2C9 | |
| SCHEMBL1431165 | 0.80 | IKBKB (0.46) | CDK9CCNT1IKBKBCHUKCYP2C9 | |
| SCHEMBL3412546 | 0.80 | IKBKB (0.46) | CDK9CCNT1IKBKBCHUKCYP2C9 | |
| SCHEMBL13981498 | 0.77 | CDK9 (0.50) | CDK9CCNT1IKBKBCHUKCYP2C9 | |
| SCHEMBL15652643 | 0.76 | IKBKB (0.46) | CDK9CCNT1IKBKBCHUKCYP2C9 | |
| SCHEMBL855607 | 0.74 | IKBKB (0.48) | CDK9IKBKBCHUKCSF1RGSK3B | |
| SCHEMBL3415636 | 0.74 | CDK9 (0.50) | CDK9CCNT1CSF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2069341-B1 | PYRROLO[2, 3-B]PYRIDIN-4-YL-BENZENESULFONAMIDE COMPOUNDS AS IKK2 INHIBITORS | GLAXO GROUP LTD (GB) | 2010-12-29 | — | — | EP | disclosed |