Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.74 |
| ▸ | TAAR1 | Q96RJ0 | 5/20 | 0.61 |
| ▸ | LOXL2 | Q9Y4K0 | 6/20 | 0.52 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.46 |
| ▸ | ABAT | P80404 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1646200 | 0.92 | LOXL2 (0.60) | HRH3TAAR1LOXL2ABATMAOB | |
| SCHEMBL2274647 | 0.86 | HRH3 (1.00) | HRH3TAAR1LOXL2CYP2A6ADRB2 | |
| SCHEMBL9552726 | 0.86 | HRH3 (0.47) | HRH3TAAR1MAOB | |
| SCHEMBL9510277 | 0.86 | HRH3 (0.47) | HRH3TAAR1MAOB | |
| SCHEMBL4415525 | 0.79 | LOXL2 (0.84) | HRH3TAAR1LOXL2CYP2A6ADRB2 | |
| Hydrochloric Acid SCHEMBL20497365 | 0.77 | LOXL2 (0.80) | HRH3TAAR1LOXL2CYP2A6ADRB2 | |
| SCHEMBL15828 | 0.76 | HRH3 (0.79) | HRH3TAAR1LOXL2ADRB2ABAT | |
| SCHEMBL1338455 | 0.76 | HRH3 (0.35) | HRH3TAAR1LOXL2 | |
| SCHEMBL22202237 | 0.76 | TAAR1 (1.00) | HRH3TAAR1LOXL2CYP2A6ADRB2 | |
| SCHEMBL22291708 | 0.76 | TAAR1 (1.00) | HRH3TAAR1LOXL2CYP2A6ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2258688-A1 | Pyridinone derivatives for treatment of atherosclerosis | SmithKline Beecham Limited (GB) | 2010-12-08 | — | — | EP | disclosed |