Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 6/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | TP53 | P04637 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL755125 | 0.83 | MEN1 (0.60) | MEN1KMT2AHDAC3ALDH1A1SMN1; SMN2 | |
| SCHEMBL23801091 | 0.83 | MEN1 (0.60) | MEN1KMT2AHDAC3ALDH1A1SMN1; SMN2 | |
| SCHEMBL16622739 | 0.81 | MEN1 (0.48) | MEN1KMT2AALDH1A1SMN1; SMN2PKM | |
| SCHEMBL581489 | 0.79 | MEN1 (0.68) | MEN1KMT2AALDH1A1SMN1; SMN2PKM | |
| SCHEMBL23800758 | 0.77 | MEN1 (0.54) | MEN1KMT2AHDAC3ALDH1A1SMN1; SMN2 | |
| SCHEMBL10053368 | 0.72 | MEN1 (0.55) | MEN1KMT2AALDH1A1SMN1; SMN2PKM | |
| SCHEMBL9010787 | 0.72 | MEN1 (0.72) | MEN1KMT2AALDH1A1SMN1; SMN2PKM | |
| SCHEMBL18094478 | 0.72 | MEN1 (0.58) | MEN1KMT2AALDH1A1SMN1; SMN2PKM | |
| SCHEMBL11985611 | 0.72 | KMT2A (0.55) | MEN1KMT2AHDAC3ALDH1A1SMN1; SMN2 | |
| SCHEMBL18026626 | 0.71 | ALDH1A1 (0.62) | MEN1KMT2AALDH1A1SMN1; SMN2PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2266958-B1 | Antiviral agent | SHIONOGI & CO (JP) | 2017-03-15 | — | — | EP | disclosed |
| EP-2266958-A1 | Antiviral agent | SHIONOGI & CO., LTD. (JP) | 2010-12-29 | — | — | EP | disclosed |