Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 9/20 | 0.36 |
| ▸ | CNR1 | P21554 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5721034 | 0.89 | CNR2 (0.46) | CNR2CNR1HRH3 | |
| SCHEMBL5721011 | 0.89 | CNR2 (0.46) | CNR2CNR1HRH3 | |
| SCHEMBL2123598 | 0.82 | CNR2 (0.37) | CNR2CNR1HRH3 | |
| SCHEMBL2123594 | 0.82 | CNR2 (0.37) | CNR2CNR1HRH3 | |
| SCHEMBL15194476 | 0.81 | CNR2 (0.36) | CNR2CNR1HRH3 | |
| SCHEMBL20458217 | 0.81 | CNR2 (0.41) | CNR2CNR1HRH3 | |
| SCHEMBL15194404 | 0.80 | CNR2 (0.40) | CNR2CNR1KDM4E | |
| SCHEMBL3965711 | 0.80 | CNR2 (0.34) | CNR2CNR1PARP1 | |
| Lithium Ion SCHEMBL15193830 | 0.79 | CNR2 (0.36) | CNR2CNR1HRH3 | |
| SCHEMBL1767824 | 0.76 | CA12 (0.36) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2443107-B1 | AZETIDINE 2 -CARBOXAMIDE DERIVATIVES WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INT (DE) | 2018-08-08 | — | — | EP | disclosed |
| WO-2010147791-A1 | AZETIDINE 2 -CARBOXAMIDE DERIVATIVES WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-12-23 | — | — | WO | disclosed |