Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 12/20 | 0.46 |
| ▸ | CNR1 | P21554 | 7/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5721011 | 1.00 | CNR2 (0.46) | CNR2CNR1HRH3POLBHSD11B1 | |
| SCHEMBL13015332 | 0.89 | CNR2 (0.36) | CNR2CNR1HRH3 | |
| SCHEMBL16323018 | 0.87 | CNR2 (0.35) | CNR2CNR1POLB | |
| SCHEMBL15665283 | 0.87 | CNR2 (0.35) | CNR2CNR1POLB | |
| SCHEMBL15665554 | 0.87 | CNR2 (0.35) | CNR2CNR1POLB | |
| SCHEMBL7020161 | 0.85 | CNR2 (0.40) | CNR2CNR1POLB | |
| SCHEMBL2573056 | 0.84 | CNR2 (0.47) | CNR2CNR1 | |
| SCHEMBL2573057 | 0.84 | CNR2 (0.47) | CNR2CNR1 | |
| SCHEMBL7021731 | 0.83 | CNR2 (0.41) | CNR2CNR1POLB | |
| SCHEMBL10979486 | 0.83 | CNR2 (0.41) | CNR2CNR1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1670786-A1 | QUINAZOLINE DERIVATIVES | Astrazeneca AB (SE) | 2006-06-21 | — | — | EP | disclosed |
| WO-2005030757-A1 | QUINAZOLINE DERIVATIVES | ASTRAZENECA AB (SE) | 2005-04-07 | — | — | WO | disclosed |