Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | F13A1 | P00488 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | CA4 | P22748 | 2/20 | 0.36 |
| ▸ | CA6 | P23280 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | CA5A | P35218 | 2/20 | 0.36 |
| ▸ | THPO | P40225 | 2/20 | 0.36 |
| ▸ | CA7 | P43166 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.36 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CASP2 | P42575 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3457117 | 1.00 | GBA1 (0.41) | GBA1TSHRALDH1A1TDP1CYP1A2 | |
| Ammonia Solution, Strong SCHEMBL10961064 | 0.97 | GBA1 (0.40) | GBA1TSHRALDH1A1TDP1CYP1A2 | |
| SCHEMBL7940472 | 0.97 | TSHR (0.43) | GBA1TSHRALDH1A1TDP1CYP1A2 | |
| SCHEMBL9752430 | 0.97 | TSHR (0.43) | GBA1TSHRALDH1A1TDP1CYP1A2 | |
| SCHEMBL3954846 | 0.88 | ALDH1A1 (0.39) | GBA1TSHRALDH1A1TDP1CYP1A2 | |
| SCHEMBL8090548 | 0.88 | ALDH1A1 (0.39) | GBA1TSHRALDH1A1TDP1CYP1A2 | |
| SCHEMBL8011003 | 0.88 | ALDH1A1 (0.39) | GBA1TSHRALDH1A1TDP1CYP1A2 | |
| SCHEMBL11414958 | 0.88 | CA12 (0.50) | GBA1TSHRALDH1A1TDP1CYP1A2 | |
| SCHEMBL7775965 | 0.88 | CA12 (0.56) | TSHRCYP1A2CA12F13A1CA2 | |
| SCHEMBL1707503 | 0.88 | TSHR (0.45) | GBA1TSHRALDH1A1TDP1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2264006-A1 | Process for the preparation of tertiary amines from primary amines and nitriles | Invista Technologies S.à.r.l. (CH) | 2010-12-22 | — | — | EP | disclosed |
| EP-1900724-A2 | Process for the preparation of tertiary amines from primary amines and nitriles | Invista Technologies S.a.r.l. (CH) | 2008-03-19 | — | — | EP | disclosed |