Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 3/20 | 0.42 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.39 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.39 |
| ▸ | AXL | P30530 | 1/20 | 0.39 |
| ▸ | KMO | O15229 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 9/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 9/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | PSD | A5PKW4 | 1/20 | 0.36 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16361130 | 0.92 | MEN1 (0.45) | MKNK1MKNK2MEN1PSIP1AXL | |
| SCHEMBL13016493 | 0.88 | MKNK1 (0.42) | MKNK1MKNK2MEN1PSIP1AXL | |
| SCHEMBL15827384 | 0.82 | CYP19A1 (0.41) | MKNK1MKNK2MEN1PSIP1AXL | |
| SCHEMBL15827379 | 0.82 | NPY5R (0.41) | NPY5RMKNK1MKNK2MEN1PSIP1 | |
| SCHEMBL18266049 | 0.81 | CYP1A1 (0.31) | MEN1CYP1A2CYP2A6CYP3A4 | |
| SCHEMBL19598397 | 0.80 | CYP11B1 (0.35) | MKNK1MKNK2MEN1PSIP1AXL | |
| SCHEMBL16002404 | 0.80 | KMO (0.34) | MKNK1MKNK2MEN1PSIP1AXL | |
| SCHEMBL5527335 | 0.79 | CYP2A6 (0.60) | NPY5RMKNK1MKNK2MEN1PSIP1 | |
| SCHEMBL19598213 | 0.79 | CYP2A6 (0.37) | MKNK1MKNK2MEN1PSIP1AXL | |
| SCHEMBL19310302 | 0.78 | MEN1 (0.34) | MKNK1MKNK2MEN1PSIP1AXL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010151389-A1 | PROCESS FOR MAKING ORGANIC COMPOUNDS AND THE ORGANIC COMPOUNDS MADE THEREFROM | GENERAL ELECTRIC COMPANY (US) | 2010-12-29 | — | — | WO | disclosed |