Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.83 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.83 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.83 |
| ▸ | NQO2 | P16083 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.51 |
| ▸ | DHODH | Q02127 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16687605 | 1.00 | KDM4E (0.83) | KDM4EALDH1A1L3MBTL1NQO2TDP1 | |
| SCHEMBL18082998 | 0.97 | KDM4E (0.77) | KDM4EALDH1A1L3MBTL1NQO2TDP1 | |
| SCHEMBL31415566 | 0.91 | KDM4E (1.00) | KDM4EALDH1A1L3MBTL1NQO2TDP1 | |
| SCHEMBL31070213 | 0.91 | KDM4E (1.00) | KDM4EALDH1A1L3MBTL1NQO2TDP1 | |
| SCHEMBL31070206 | 0.91 | KDM4E (1.00) | KDM4EALDH1A1L3MBTL1NQO2TDP1 | |
| SCHEMBL1104817 | 0.91 | KDM4E (1.00) | KDM4EALDH1A1L3MBTL1NQO2TDP1 | |
| SCHEMBL825060 | 0.89 | KDM4E (0.96) | KDM4EALDH1A1L3MBTL1NQO2TDP1 | |
| SCHEMBL18082983 | 0.89 | KDM4E (0.65) | KDM4EALDH1A1L3MBTL1NQO2TDP1 | |
| SCHEMBL12553477 | 0.89 | KDM4E (0.96) | KDM4EALDH1A1L3MBTL1NQO2TDP1 | |
| SCHEMBL18082999 | 0.88 | KDM4E (0.64) | KDM4EALDH1A1L3MBTL1NQO2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9434701-B2 | Aminoquinoxaline derivatives for treatment of neurodegenerative diseases | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2016-09-06 | — | — | US | disclosed |
| EP-1501907-B1 | SOLUTION-PROCESSABLE PHOSPHORESCENT MATERIALS | CAMBRIDGE ENTPR LTD (GB) | 2016-07-27 | — | — | EP | disclosed |
| US-9023978-B2 | Solution-processable phosphorescent materials | CAMBRIDGE ENTERPRISE LTD. (GB) | 2015-05-05 | — | — | US | disclosed |
| US-9023978-B2 | Solution-processable phosphorescent materials | CAMBRIDGE ENTERPRISE LTD. (GB) | 2015-05-05 | — | — | US | disclosed |
| EP-2264123-A2 | Solution-processable phosphorescent materials | Cambridge Display Technology Limited (GB) | 2010-12-22 | — | — | EP | disclosed |