SCHEMBL825060

SCHEMBL825060

Cc1ccc2nc(-c3ccc(-c4nc5ccc(C)cc5nc4-c4ccccc4)cc3)c(-c3ccccc3)nc2c1

nearest known ligand 0.96

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.96
ALDH1A1 P00352 6/20 0.96
L3MBTL1 Q9Y468 5/20 0.96
TDP1 Q9NUW8 3/20 0.75
NQO2 P16083 1/20 0.64
KMT2A Q03164 2/20 0.59
ATM Q13315 1/20 0.59
TLR9 Q9NR96 1/20 0.59
MAPT P10636 3/20 0.58
GAA P10253 3/20 0.58
HPGD P15428 2/20 0.58
LMNA P02545 4/20 0.56
RAB9A P51151 2/20 0.56
SMN1; SMN2 Q16637 2/20 0.56
DHODH Q02127 1/20 0.55
NPC1 O15118 1/20 0.54
MEN1 O00255 1/20 0.53
NPSR1 Q6W5P4 1/20 0.53
PSMB5 P28074 1/20 0.50
PDE10A Q9Y233 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12553477 1.00 KDM4E (0.96) KDM4EALDH1A1L3MBTL1TDP1NQO2
SCHEMBL18083001 0.98 ALDH1A1 (0.93) KDM4EALDH1A1L3MBTL1TDP1NQO2
SCHEMBL1104817 0.98 KDM4E (1.00) KDM4EALDH1A1L3MBTL1TDP1NQO2
SCHEMBL31070213 0.98 KDM4E (1.00) KDM4EALDH1A1L3MBTL1TDP1NQO2
SCHEMBL31415566 0.98 KDM4E (1.00) KDM4EALDH1A1L3MBTL1TDP1NQO2
SCHEMBL31070206 0.98 KDM4E (1.00) KDM4EALDH1A1L3MBTL1TDP1NQO2
SCHEMBL21397101 0.94 ALDH1A1 (0.93) KDM4EALDH1A1L3MBTL1TDP1NQO2
SCHEMBL12595573 0.91 ALDH1A1 (0.79) KDM4EALDH1A1L3MBTL1TDP1NQO2
SCHEMBL12595616 0.91 ALDH1A1 (0.79) KDM4EALDH1A1L3MBTL1TDP1NQO2
SCHEMBL18082998 0.90 KDM4E (0.77) KDM4EALDH1A1L3MBTL1TDP1NQO2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8142956-B2 Fuel cell NITTO DENKO CORPORATION (JP) 2012-03-27 US disclosed
US-8142956-B2 Fuel cell NITTO DENKO CORPORATION (JP) 2012-03-27 US disclosed
US-20080286645-A1 ELECTROCHMICAL CELL ELECTRODE AND ELECTROCHEMICAL CELL NEC TOKIN CORPORATION (JP) 2008-11-20 US disclosed
US-20080226985-A1 High temperature cycle properties, inexpensive electrode material; polyphenylquinoxaline active material; secondary batteries, electric double layer capacitors, redox capacitors, condensers NEC TOKIN CORPORATION (JP) 2008-09-18 US disclosed
US-20080063940-A1 CELL ELECTRODE AND ELECTROCHEMICAL CELL THEREWITH NEC TOKIN CORPORATION (JP) 2008-03-13 US disclosed
US-7309544-B2 Cell electrode and electrochemical cell therewith NEC TOKIN CORPORATION (JP) 2007-12-18 US disclosed
US-7255779-B2 High electromotive force and capacity as an electrochemical cell using proton as an electric charge carrier IHARA CHEMICAL INDUSTRY CO., LTD. (JP) 2007-08-14 US disclosed
US-20070172731-A1 PROTON-CONDUCTING POLYMER BATTERY NEC TOKIN CORPORATION (JP) 2007-07-26 US disclosed
US-7230069-B2 Polymers and electrochemical cell therewith NEC TOKIN CORPORATION (JP) 2007-06-12 US disclosed
US-7226695-B2 Polymerr\\conductive electrode, dehydration condensation polymer with tetramine derivatives of quinoxaline derivatives for batteries SHOWA DENKO K.K. (JP) 2007-06-05 US disclosed
US-20070095656-A1 Method for purification of indole derivative trimer, electrode active substance comprising the purified trimer, method for manufacturing the electrode active substance, and electrochemical cell using the same NEC TOKIN CORPORATION (JP) 2007-05-03 US disclosed
US-7205071-B2 Having high rate and cycle characteristics as well as sufficient electromotive force and capacity NEC TOKIN CORPORATION (JP) 2007-04-17 US disclosed
US-7169509-B2 Electrode and electrochemical cell therewith NEC TOKIN CORPORATION (JP) 2007-01-30 US disclosed