SCHEMBL1301829

SCHEMBL1301829

c1ccc(-c2nc3ccc(-c4ccc5nc(-c6ccccc6)c(-c6ccccc6)nc5c4)cc3nc2-c2ccccc2)cc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.68
KDM4E B2RXH2 7/20 0.68
L3MBTL1 Q9Y468 5/20 0.68
KMT2A Q03164 3/20 0.68
ATM Q13315 1/20 0.68
TLR9 Q9NR96 1/20 0.68
HPGD P15428 4/20 0.61
GAA P10253 2/20 0.61
NPC1 O15118 1/20 0.61
RAB9A P51151 1/20 0.61
SMN1; SMN2 Q16637 1/20 0.61
LMNA P02545 5/20 0.61
TDP1 Q9NUW8 3/20 0.61
MEN1 O00255 2/20 0.61
PIK3R1 P27986 1/20 0.61
PIK3CA P42336 1/20 0.61
NPSR1 Q6W5P4 1/20 0.55
MAPT P10636 2/20 0.54
GPR55 Q9Y2T6 1/20 0.54
HTT P42858 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27734154 0.98 ALDH1A1 (0.66) ALDH1A1KDM4EL3MBTL1KMT2AATM
SCHEMBL12462566 0.98 ALDH1A1 (0.66) ALDH1A1KDM4EL3MBTL1KMT2AATM
SCHEMBL24596446 0.92 KDM4E (0.59) ALDH1A1KDM4EL3MBTL1KMT2AATM
SCHEMBL12111553 0.90 MAPK14 (0.61) ALDH1A1KDM4EL3MBTL1KMT2AATM
SCHEMBL12595616 0.90 ALDH1A1 (0.79) ALDH1A1KDM4EL3MBTL1KMT2AATM
SCHEMBL12111667 0.90 MAPK14 (0.61) ALDH1A1KDM4EL3MBTL1KMT2AATM
SCHEMBL12595573 0.90 ALDH1A1 (0.79) ALDH1A1KDM4EL3MBTL1KMT2AATM
SCHEMBL12111547 0.90 MAPK14 (0.61) ALDH1A1KDM4EL3MBTL1KMT2AATM
SCHEMBL24184940 0.90 ALDH1A1 (0.58) ALDH1A1KDM4EL3MBTL1KMT2AATM
SCHEMBL12111626 0.90 MAPK14 (0.61) ALDH1A1KDM4EL3MBTL1KMT2AATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2113133-B1 LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE AND QUINOXALINE DERIVATIVE SEMICONDUCTOR ENERGY LAB (JP) 2013-04-24 EP claimed
US-7875879-B2 Light-emitting element, light-emitting device, electronic device and quinoxaline derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2011-01-25 US claimed
EP-2113133-A1 LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE AND QUINOXALINE DERIVATIVE Semiconductor Energy Laboratory Co, Ltd. (JP) 2009-11-04 EP claimed
US-20080217608-A1 Light-Emitting Element, Light-Emitting Device, Electronic Device and Quinoxaline Derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2008-09-11 US claimed
WO-2008102713-A1 LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE AND QUINOXALINE DERIVATIVE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2008-08-28 WO claimed
JP-6207169-A None JP disclosed
EP-3931184-A1 METHOD FOR PRODUCING QUINOXALINES Technische Universität Wien (AT) 2022-01-05 EP disclosed
US-10633369-B2 Method of inhibiting DYRK1B 4 SC AG (DE) 2020-04-28 US disclosed
US-20180201606-A1 METHOD OF INHIBITING DYRK1B 4 SC AG (DE) 2018-07-19 US disclosed
US-9951050-B2 Method of inhibiting DYRK1B 4 SC AG (DE) 2018-04-24 US disclosed
US-9431574-B2 Light-emitting device including color filter and black matrix SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-08-30 US disclosed
EP-1973386-B1 LIGHT-EMITTING DEVICE AND ELECTRONIC DEVICE SEMICONDUCTOR ENERGY LAB (JP) 2015-11-11 EP disclosed
US-20090114926-A1 Light-emitting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2009-05-07 US disclosed
US-20080231177-A1 Light-Emitting Device and Electronic Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2008-09-25 US disclosed
EP-1973386-A2 Light-emitting device and electronic device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2008-09-24 EP disclosed
US-20080217608-A1 Light-Emitting Element, Light-Emitting Device, Electronic Device and Quinoxaline Derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2008-09-11 US disclosed
WO-2008102713-A1 LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE AND QUINOXALINE DERIVATIVE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2008-08-28 WO disclosed
US-20070141393-A1 Amino anthracene compounds in OLED devices EASTMAN KODAK COMPANY 2007-06-21 US disclosed
US-20070141393-A1 Amino anthracene compounds in OLED devices EASTMAN KODAK COMPANY 2007-06-21 US disclosed
JP-H06207169-A ORGANIC ELECTROLUMINESCENCE ELEMENT IDEMITSU KOSAN CO LTD 1994-07-26 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10633369-B2 Method of inhibiting DYRK1B SMO, GLI1, GRK2 ALDH1A1 3401/4885KDM4E 996/4885L3MBTL1 3046/4885
US-20180201606-A1 METHOD OF INHIBITING DYRK1B SMO, GLI1, GRK2 ALDH1A1 3401/4885KDM4E 996/4885L3MBTL1 3046/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.