Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.64 |
| ▸ | IDO1 | P14902 | 1/20 | 0.57 |
| ▸ | TDO2 | P48775 | 1/20 | 0.57 |
| ▸ | ABCB1 | P08183 | 6/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.45 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29932788 | 0.84 | IRAK4 (0.62) | IRAK4IDO1TDO2ABCB1ALDH1A1 | |
| SCHEMBL19388312 | 0.84 | ABCB1 (0.49) | IRAK4ABCB1ALDH1A1KDM4ELMNA | |
| SCHEMBL28947632 | 0.84 | ABCB1 (0.49) | IRAK4IDO1TDO2ABCB1ALDH1A1 | |
| SCHEMBL11442930 | 0.84 | IRAK4 (0.62) | IRAK4IDO1TDO2ABCB1ALDH1A1 | |
| SCHEMBL27571514 | 0.83 | ABCB1 (0.48) | IRAK4IDO1TDO2ABCB1ALDH1A1 | |
| SCHEMBL27958806 | 0.81 | IRAK4 (0.68) | IRAK4IDO1TDO2ALDH1A1ACHE | |
| SCHEMBL27543107 | 0.81 | ABCB1 (0.47) | IRAK4IDO1TDO2ABCB1ALDH1A1 | |
| SCHEMBL7088362 | 0.81 | IRAK4 (0.72) | IRAK4IDO1TDO2ALDH1A1ACHE | |
| SCHEMBL2094692 | 0.81 | IRAK4 (0.72) | IRAK4IDO1TDO2ABCB1ALDH1A1 | |
| SCHEMBL28812389 | 0.81 | ABCB1 (0.55) | ABCB1ALDH1A1KDM4ELMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118530241-A | Thioether substituted diphenyl pyrrolopyrrole diketone and preparation method and application thereof | 山东凯瑞尔光电科技有限公司 | 2024-08-23 | — | — | CN | disclosed |
| CN-116969953-A | Diphenyl pyrrolo-pyrrole-dione derivative, pigment composition and application thereof | 山东凯瑞尔光电科技有限公司 | 2023-10-31 | — | — | CN | disclosed |
| US-9617246-B2 | Thioether-piperidinyl orexin receptor antagonists | MERCK SHARP & DOHME CORP. (US) | 2017-04-11 | — | — | US | disclosed |
| US-20100331348-A1 | TROPANE DERIVATIVES USEFUL AS PESTICIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2010-12-30 | — | — | US | disclosed |
| US-20100331348-A1 | TROPANE DERIVATIVES USEFUL AS PESTICIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2010-12-30 | — | — | US | disclosed |
| CN-1090617-C | Pyrrole derivatives and pharmaceutical compositions | NIPPON SHINYAKU CO LTD (JP) | 2002-09-11 | — | — | CN | disclosed |
| CN-1349796-A | Pyrrole derivatives and medicine composition | NIPPON SHINYAKU CO LTD (JP) | 2002-05-22 | — | — | CN | disclosed |
| CN-1186485-A | Pyrrole derivatives and pharmaceutical compositions | NIPPON SHINYAKU CO LTD (JP) | 1998-07-01 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100331348-A1 | TROPANE DERIVATIVES USEFUL AS PESTICIDES | DDT, ACHE, TPM3 | IRAK4 4750/4885IDO1 515/4885TDO2 150/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.