Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.57 |
| ▸ | CA2 | P00918 | 4/20 | 0.57 |
| ▸ | CA7 | P43166 | 2/20 | 0.57 |
| ▸ | CA9 | Q16790 | 2/20 | 0.57 |
| ▸ | CA12 | O43570 | 1/20 | 0.57 |
| ▸ | CA4 | P22748 | 1/20 | 0.57 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.57 |
| ▸ | IDO1 | P14902 | 3/20 | 0.47 |
| ▸ | TDO2 | P48775 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29005947 | 0.82 | CA1 (0.48) | CA1CA2CA7CA9CA12 | |
| SCHEMBL22827469 | 0.82 | KRAS (0.44) | CA1CA2CA7CA9CA12 | |
| SCHEMBL22827153 | 0.82 | CA1 (0.42) | CA1CA2CA7CA9CA12 | |
| SCHEMBL8879882 | 0.81 | CA1 (0.52) | CA1CA2CA7CA9CA12 | |
| SCHEMBL27772307 | 0.81 | CA1 (0.52) | CA1CA2CA7CA9CA12 | |
| SCHEMBL27772296 | 0.81 | CA1 (0.52) | CA1CA2CA7CA9CA12 | |
| SCHEMBL28238041 | 0.81 | CA1 (0.52) | CA1CA2CA7CA9CA12 | |
| SCHEMBL27999515 | 0.81 | ALDH1A1 (0.43) | CA1CA2CA7CA9CA12 | |
| SCHEMBL17593428 | 0.79 | IRAK4 (0.44) | CA1CA2CA7CA9ALDH1A1 | |
| SCHEMBL31511214 | 0.79 | ALDH1A1 (0.52) | ALDH1A1TDP1L3MBTL1MAPK1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9475756-B2 | Difluoromethylation of aryl and vinyl iodides | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2016-10-25 | — | — | US | disclosed |
| US-9475756-B2 | Difluoromethylation of aryl and vinyl iodides | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2016-10-25 | — | — | US | disclosed |
| US-9475756-B2 | Difluoromethylation of aryl and vinyl iodides | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2016-10-25 | — | — | US | disclosed |
| US-20150045580-A1 | DIFLUOROMETHYLATION OF ARYL AND VINYL IODIDES | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2015-02-12 | — | — | US | disclosed |
| US-20150045580-A1 | DIFLUOROMETHYLATION OF ARYL AND VINYL IODIDES | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2015-02-12 | — | — | US | disclosed |
| US-20150045580-A1 | DIFLUOROMETHYLATION OF ARYL AND VINYL IODIDES | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2015-02-12 | — | — | US | disclosed |
| WO-2013134296-A1 | DIFLUOROMETHYLATION OF ARYL AND VINYL IODIDES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2013-09-12 | — | — | WO | disclosed |
| CN-101547922-B | Pyrido[4,3-d]pyrimidin-4(3h)-one derivatives as calcium receptor antagonists | PFIZER PROD INC | 2012-06-20 | — | — | CN | disclosed |
| US-20100331310-A1 | BICYCLOAMINE DERIVATIVES | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2010-12-30 | — | — | US | disclosed |
| CN-101910169-A | Bicyclic amine derivatives | EISAI R&D MAN CO LTD | 2010-12-08 | — | — | CN | disclosed |
| CN-101547922-A | Pyrido[4,3-d]pyrimidin-4(3H)-one derivatives as calcium receptor antagonists | PFIZER PRODUCT INC (US) | 2009-09-30 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100331310-A1 | BICYCLOAMINE DERIVATIVES | SCN1B, KCNJ2, KCNH2 | CA1 2021/4885CA2 883/4885CA7 3048/4885 |
| US-20150045580-A1 | DIFLUOROMETHYLATION OF ARYL AND VINYL IODIDES | CUL2, CUL3, CYP4F2 | CA1 3188/4885CA2 3435/4885CA7 3209/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.