Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 3/20 | 0.68 |
| ▸ | PRKDC | P78527 | 3/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.67 |
| ▸ | FYN | P06241 | 10/20 | 0.60 |
| ▸ | LYN | P07948 | 3/20 | 0.60 |
| ▸ | BLK | P51451 | 3/20 | 0.60 |
| ▸ | ABL1 | P00519 | 2/20 | 0.59 |
| ▸ | SRC | P12931 | 4/20 | 0.57 |
| ▸ | BTK | Q06187 | 2/20 | 0.57 |
| ▸ | YES1 | P07947 | 2/20 | 0.57 |
| ▸ | FGR | P09769 | 2/20 | 0.57 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.57 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.57 |
| ▸ | EGFR | P00533 | 1/20 | 0.57 |
| ▸ | LCK | P06239 | 1/20 | 0.57 |
| ▸ | HCK | P08631 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29678005 | 0.87 | PIK3CD (0.74) | PIK3CDPRKDCCYP1A2MAPK1FYN | |
| SCHEMBL13019687 | 0.83 | CYP1A2 (0.75) | PIK3CDPRKDCCYP1A2MAPK1MEN1 | |
| SCHEMBL29175926 | 0.81 | PIK3CD (0.69) | PIK3CDPRKDCCYP1A2MAPK1FYN | |
| SCHEMBL30387431 | 0.81 | PIK3CD (1.00) | PIK3CDPRKDCABL1SRCEGFR | |
| SCHEMBL29999094 | 0.81 | PIK3CD (0.69) | PIK3CDPRKDCCYP1A2MAPK1FYN | |
| SCHEMBL13019926 | 0.80 | FYN (0.70) | PIK3CDPRKDCCYP1A2MAPK1MEN1 | |
| SCHEMBL13019782 | 0.80 | CYP1A2 (1.00) | PIK3CDPRKDCCYP1A2MAPK1MEN1 | |
| SCHEMBL13019685 | 0.80 | PIK3CD (0.73) | PIK3CDPRKDCCYP1A2MAPK1MEN1 | |
| SCHEMBL13019688 | 0.80 | PIK3CD (0.68) | PIK3CDPRKDCCYP1A2MAPK1MEN1 | |
| SCHEMBL13019998 | 0.80 | FYN (0.77) | PIK3CDPRKDCCYP1A2MAPK1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100331297-A1 | MODULATION OF PROTEIN TRAFFICKING | FOLDRX PHARMACEUTICALS, INC. (US) | 2010-12-30 | — | — | US | disclosed |
| US-20100331297-A1 | MODULATION OF PROTEIN TRAFFICKING | FOLDRX PHARMACEUTICALS, INC. (US) | 2010-12-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100331297-A1 | MODULATION OF PROTEIN TRAFFICKING | RAB1A, COPB1, GOLT1B | PIK3CD 2217/4885PRKDC 1498/4885CYP1A2 4534/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.