SCHEMBL130214

SCHEMBL130214

CCCCCCCC#CO

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN7 P35236 5/20 0.52
HMGCR P04035 3/20 0.52
RECQL P46063 2/20 0.47
TDP1 Q9NUW8 2/20 0.47
TSHR P16473 2/20 0.44
THRB P10828 1/20 0.44
MEN1 O00255 2/20 0.43
ALDH1A1 P00352 2/20 0.43
KMT2A Q03164 2/20 0.43
KDM4E B2RXH2 1/20 0.43
USP2 O75604 1/20 0.43
POLB P06746 1/20 0.43
MAPT P10636 1/20 0.43
HPGD P15428 1/20 0.43
ALOX12 P18054 1/20 0.43
BLM P54132 1/20 0.43
MCL1 Q07820 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
LMNA P02545 2/20 0.41
HSD17B10 Q99714 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL129776 1.00 PTPN7 (0.52) PTPN7HMGCRRECQLTDP1TSHR
SCHEMBL9361038 1.00 PTPN7 (0.52) PTPN7HMGCRRECQLTDP1TSHR
SCHEMBL448226 1.00 PTPN7 (0.52) PTPN7HMGCRRECQLTDP1TSHR
SCHEMBL128297 1.00 PTPN7 (0.52) PTPN7HMGCRRECQLTDP1TSHR
SCHEMBL448860 1.00 PTPN7 (0.52) PTPN7HMGCRRECQLTDP1TSHR
SCHEMBL126745 1.00 PTPN7 (0.52) PTPN7HMGCRRECQLTDP1TSHR
SCHEMBL448474 1.00 PTPN7 (0.52) PTPN7HMGCRRECQLTDP1TSHR
SCHEMBL128390 1.00
SCHEMBL130583 1.00 PTPN7 (0.52) PTPN7HMGCRRECQLTDP1TSHR
SCHEMBL31423438 1.00 PTPN7 (0.52) PTPN7HMGCRRECQLTDP1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113388360-B Two-component polyurethane adhesive capable of being rapidly cured in long opening time 杭州之江新材料有限公司 2022-10-28 CN claimed
EP-4096442-A1 SOLID ADSORBENT COMPOSITIONS FOR PURIFYING LIQUIDS The Dallas Group of America, Inc. (US) 2022-12-07 EP disclosed
CN-113388360-B Two-component polyurethane adhesive capable of being rapidly cured in long opening time 杭州之江新材料有限公司 2022-10-28 CN disclosed
CN-110791363-B Fully synthetic cutting fluid and preparation method thereof 佳化化学(上海)有限公司 2022-05-27 CN disclosed
CN-103772082-B The method of aldehydes or ketones prepared by a kind of dioxygen oxidation alcohol EAST CHINA NORMAL UNIVERSITY (CN) 2016-01-20 CN disclosed
US-9029069-B2 Resist underlayer film-forming composition and method for forming pattern JSR CORPORATION (JP) 2015-05-12 US disclosed
US-8859185-B2 Resist underlayer film-forming composition JSR CORPORATION (JP) 2014-10-14 US disclosed
EP-1512397-B1 O-SUBSTITUTED HYDROXYARYL DERIVATIVES INST MED MOLECULAR DESIGN INC (JP) 2014-10-08 EP disclosed
CN-103772082-A Method for preparing aldehyde or ketone by oxidizing alcohol by using oxygen UNIV EAST CHINA NORMAL 2014-05-07 CN disclosed
CN-102336619-B Method for preparing aldehyde or ketone by oxidizing alcohol with oxygen UNIV EAST CHINA NORMAL 2014-01-29 CN disclosed
EP-1512397-A1 O-SUBSTITUTED HYDROXYARYL DERIVATIVES Institute of Medicinal Molecular Design, Inc. (JP) 2005-03-09 EP disclosed
EP-1512396-A1 INHIBITORS AGAINST THE ACTIVATION OF AP-1 AND NFAT Institute of Medicinal Molecular Design, Inc. (JP) 2005-03-09 EP disclosed
EP-1510210-A1 IMMUNITY-RELATED PROTEIN KINASE INHIBITORS Institute of Medicinal Molecular Design, Inc. (JP) 2005-03-02 EP disclosed
EP-1510207-A1 THERAPEUTIC DRUG FOR DIABETES Institute of Medicinal Molecular Design, Inc. (JP) 2005-03-02 EP disclosed
US-20040259877-A1 Inhibitors against the production and release of inflammatory cytokines INSTITUTE OF MEDICINAL MOLECULAR DESIGN, INC. (JP) 2004-12-23 US disclosed
EP-1352650-A1 INHIBITORS AGAINST THE PRODUCTION AND RELEASE OF INFLAMMATORY CYTOKINES Institute of Medicinal Molecular Design, Inc. (JP) 2003-10-15 EP disclosed
EP-0374765-B1 2,3-Disubstituted-4-hydroxyquinoline derivatives and process for preparing the same MEIJI SEIKA KAISHA (JP) 1994-06-22 EP disclosed
US-5194617-A Leukotriene antagonist, antiasthma, improved blood circulation to brain MEIJI SEIKA KAISHA, LTD. (JP) 1993-03-16 US disclosed
EP-0374765-A1 2,3-Disubstituted-4-hydroxyquinoline derivatives and process for preparing the same MEIJI SEIKA KAISHA LTD. (JP) 1990-06-27 EP disclosed
US-4877891-A INTERMEDIATES FOR E7,Z-9-DODECADIENYL ACETATE BASF AKTIENGESELLSCHAFT (DE) 1989-10-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040259877-A1 Inhibitors against the production and release of inflammatory cytokines NFKBIA, IL1B, IKBKB PTPN7 865/4885HMGCR 2007/4885RECQL 3716/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.