Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK10 | P53779 | 1/20 | 0.45 |
| ▸ | TNF | P01375 | 1/20 | 0.45 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.43 |
| ▸ | CSNK2A2 | P19784 | 5/20 | 0.43 |
| ▸ | CSNK2B | P67870 | 5/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.42 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.39 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13021752 | 1.00 | MAPK10 (0.45) | MAPK10TNFMKNK1PIK3CACSNK2A2 | |
| SCHEMBL13021754 | 1.00 | MAPK10 (0.45) | MAPK10TNFMKNK1PIK3CACSNK2A2 | |
| SCHEMBL13021744 | 1.00 | MAPK10 (0.45) | MAPK10TNFMKNK1PIK3CACSNK2A2 | |
| SCHEMBL13021784 | 0.96 | KDM4E (0.43) | MAPK10TNFMKNK1PIK3CACSNK2A2 | |
| SCHEMBL13021781 | 0.96 | KDM4E (0.43) | MAPK10TNFMKNK1PIK3CACSNK2A2 | |
| SCHEMBL13021799 | 0.96 | KDM4E (0.43) | MAPK10TNFMKNK1PIK3CACSNK2A2 | |
| SCHEMBL13021798 | 0.96 | KDM4E (0.43) | MAPK10TNFMKNK1PIK3CACSNK2A2 | |
| SCHEMBL18252357 | 0.87 | TNF (0.44) | MAPK10TNFMKNK1PIK3CACSNK2A2 | |
| SCHEMBL18252361 | 0.87 | TNF (0.44) | MAPK10TNFMKNK1PIK3CACSNK2A2 | |
| SCHEMBL17281384 | 0.86 | NOTUM (0.56) | MKNK1PIK3CANOTUMIMPDH2CHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3120396-B1 | ORGANIC ELECTROLUMINESCENT DEVICE | MERCK PATENT GMBH (DE) | 2021-06-02 | — | — | EP | disclosed |
| US-20170092875-A1 | ORGANIC ELECTROLUMINESCENT DEVICE | MERCK PATENT GMBH (DE) | 2017-03-30 | — | — | US | disclosed |
| US-20170092875-A1 | ORGANIC ELECTROLUMINESCENT DEVICE | MERCK PATENT GMBH (DE) | 2017-03-30 | — | — | US | disclosed |
| EP-2520571-B1 | 2-azatriphenylene materials for organic light emitting diodes | UNIVERSAL DISPLAY CORP (US) | 2016-08-17 | — | — | EP | disclosed |
| WO-2015139808-A1 | ORGANIC ELECTROLUMINESCENT DEVICE | MERCK PATENT GMBH (DE) | 2015-09-24 | — | — | WO | disclosed |
| US-9005771-B2 | 2-azatriphenylene materials for organic light emitting diodes | UNIVERSAL DISPLAY CORPORATION (US) | 2015-04-14 | — | — | US | disclosed |
| US-9005771-B2 | 2-azatriphenylene materials for organic light emitting diodes | UNIVERSAL DISPLAY CORPORATION (US) | 2015-04-14 | — | — | US | disclosed |
| EP-2429997-B1 | 2-AZATRIPHENYLENE MATERIALS FOR ORGANIC LIGHT EMITTING DIODES | UNIVERSAL DISPLAY CORP (US) | 2014-01-15 | — | — | EP | disclosed |
| US-20100289406-A1 | 2-AZATRIPHENYLENE MATERIALS FOR ORGANIC LIGHT EMITTING DIODES | UNIVERSAL DISPLAY CORPORATION (US) | 2010-11-18 | — | — | US | disclosed |
| US-20100289406-A1 | 2-AZATRIPHENYLENE MATERIALS FOR ORGANIC LIGHT EMITTING DIODES | UNIVERSAL DISPLAY CORPORATION (US) | 2010-11-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100289406-A1 | 2-AZATRIPHENYLENE MATERIALS FOR ORGANIC LIGHT EMITTING DIODES | DDT, NR2E3, ALKBH2 | MAPK10 4209/4885TNF 3793/4885MKNK1 2091/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.