SCHEMBL13022983

SCHEMBL13022983

Cc1ccc2c(c1)N(c1c(C)cc(C(C)(C)C)cc1C)c1ccncc1O2

nearest known ligand 0.36

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.36
CA12 O43570 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA9 Q16790 1/20 0.36
PIM1 P11309 15/20 0.33
TDP1 Q9NUW8 1/20 0.31
S1PR1 P21453 1/20 0.30
S1PR3 Q99500 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13023033 0.91 MAPT (0.34) MAPTCA12CA1CA2CA9
SCHEMBL13023016 0.91 MAPT (0.34) MAPTCA12CA1CA2CA9
SCHEMBL13022245 0.87 POLB (0.36)
SCHEMBL13023044 0.86 POLB (0.30)
SCHEMBL13023001 0.85 TDP1 (0.31) CA12CA1CA2CA9TDP1
SCHEMBL13022961 0.85 MAPT (0.32) MAPTCA12CA1CA2CA9
SCHEMBL13022249 0.84 POLB (0.33)
SCHEMBL13022298 0.84 NR1I2 (0.30)
SCHEMBL13023000 0.83 MAPT (0.30) MAPTCA12CA1CA2CA9
SCHEMBL13022928 0.83 P2RX4 (0.38) MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100286360-A1 POLYMER COMPOUND AND POLYMER LIGHT EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-11-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100286360-A1 POLYMER COMPOUND AND POLYMER LIGHT EMITTING DEVICE USING THE SAME IGF1R, SCO2, CRY1 MAPT 2367/4885CA12 2435/4885CA1 1858/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.