Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HAO1 | Q9UJM8 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13400534 | 0.88 | HAO1 (0.48) | HAO1LMNAEGFRL3MBTL1ACACB | |
| SCHEMBL13023078 | 0.84 | HAO1 (0.49) | HAO1LMNAMAP3K14EGFRL3MBTL1 | |
| SCHEMBL13023074 | 0.78 | EGFR (0.43) | HAO1LMNAEGFRL3MBTL1ALDH1A1 | |
| SCHEMBL13022987 | 0.78 | FABP7 (0.50) | HAO1LMNAMEN1KMT2ACYP3A4 | |
| SCHEMBL13023059 | 0.75 | FABP7 (0.50) | HAO1MEN1KMT2ACYP3A4CA12 | |
| SCHEMBL30092382 | 0.74 | MAP3K14 (0.45) | HAO1MAP3K14EGFRL3MBTL1ALDH1A1 | |
| SCHEMBL471131 | 0.74 | MAP3K14 (0.45) | HAO1MAP3K14EGFRL3MBTL1ALDH1A1 | |
| SCHEMBL23025722 | 0.73 | HAO1 (0.47) | HAO1LMNAMAP3K14EGFRL3MBTL1 | |
| SCHEMBL13300036 | 0.73 | EGFR (0.39) | HAO1LMNAEGFRL3MBTL1ALDH1A1 | |
| SCHEMBL11443850 | 0.72 | HAO1 (0.46) | HAO1LMNAMAP3K14EGFRL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100286353-A1 | ACETYLENE COMPOUND, SALT THEREOF, CONDENSATE THEREOF, AND COMPOSITION THEREOF | FUJIFILM CORPORATION (JP) | 2010-11-11 | — | — | US | disclosed |
| US-20100286353-A1 | ACETYLENE COMPOUND, SALT THEREOF, CONDENSATE THEREOF, AND COMPOSITION THEREOF | FUJIFILM CORPORATION (JP) | 2010-11-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100286353-A1 | ACETYLENE COMPOUND, SALT THEREOF, CONDENSATE THEREOF, AND COMPOSITION THEREOF | KAT8, HDAC10, SSRP1 | HAO1 2104/4885LMNA 413/4885MAP3K14 3061/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.