Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HAO1 | Q9UJM8 | 2/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.40 |
| ▸ | ACR | P10323 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ESR1 | P03372 | 2/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13022991 | 0.84 | HAO1 (0.50) | HAO1LMNAMAPTALDH1A1L3MBTL1 | |
| SCHEMBL14501370 | 0.80 | PRSS1 (0.48) | HAO1PRSS1ACRMAPTESR1 | |
| SCHEMBL13023050 | 0.79 | FABP7 (0.49) | HAO1PRSS1ACRMAPTESR1 | |
| SCHEMBL13066087 | 0.78 | PRSS1 (0.45) | PRSS1ACRMAPTESR1ESR2 | |
| SCHEMBL13400534 | 0.77 | HAO1 (0.48) | HAO1LMNAMAPTALDH1A1L3MBTL1 | |
| SCHEMBL13022936 | 0.76 | FABP7 (0.49) | HAO1PRSS1ACRMAPTESR1 | |
| SCHEMBL14501371 | 0.76 | ESR1 (0.50) | HAO1PRSS1ACRMAPTESR1 | |
| SCHEMBL13023070 | 0.75 | LMNA (0.47) | LMNAMAPTNR1H4L3MBTL1EGFR | |
| SCHEMBL471131 | 0.73 | MAP3K14 (0.45) | HAO1MAPTALDH1A1L3MBTL1MAP3K14 | |
| SCHEMBL30092382 | 0.73 | MAP3K14 (0.45) | HAO1MAPTALDH1A1L3MBTL1MAP3K14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100286353-A1 | ACETYLENE COMPOUND, SALT THEREOF, CONDENSATE THEREOF, AND COMPOSITION THEREOF | FUJIFILM CORPORATION (JP) | 2010-11-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100286353-A1 | ACETYLENE COMPOUND, SALT THEREOF, CONDENSATE THEREOF, AND COMPOSITION THEREOF | KAT8, HDAC10, SSRP1 | HAO1 2104/4885PRSS1 2206/4885ACR 522/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.