Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | FASN | P49327 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | PTAFR | P25105 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13023612 | 0.89 | SLC6A2 (0.46) | SLC6A2SLC6A4SLC6A3DRD2FASN | |
| SCHEMBL10552826 | 0.89 | SLC6A2 (0.48) | SLC6A2SLC6A4SLC6A3DRD2FASN | |
| SCHEMBL10552244 | 0.88 | SLC6A2 (0.43) | SLC6A2SLC6A4SLC6A3DRD2FASN | |
| SCHEMBL10552239 | 0.88 | SLC6A2 (0.43) | SLC6A2SLC6A4SLC6A3DRD2FASN | |
| SCHEMBL10634759 | 0.85 | DRD2 (0.42) | SLC6A2SLC6A4SLC6A3DRD2MAPT | |
| SCHEMBL10634754 | 0.85 | DRD2 (0.42) | SLC6A2SLC6A4SLC6A3DRD2MAPT | |
| SCHEMBL10552455 | 0.85 | FASN (0.49) | SLC6A2SLC6A4SLC6A3DRD2FASN | |
| SCHEMBL13023626 | 0.84 | SLC6A2 (0.41) | SLC6A2SLC6A4SLC6A3DRD2FASN | |
| SCHEMBL19681571 | 0.83 | SLC6A2 (0.47) | SLC6A2SLC6A4SLC6A3DRD2MAPT | |
| SCHEMBL13065539 | 0.82 | FASN (0.38) | FASNMAPTCYP2C9ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7842357-B2 | Tetrahydropyran compound, liquid crystal, composition and liquid crystal display device containing the liquid crystal composition | CHISSO CORPORATION (JP) | 2010-11-30 | — | — | US | disclosed |