SCHEMBL13023729

SCHEMBL13023729

Cc1cc(C)c(N2c3ccccc3Oc3ccoc32)c(C)c1

nearest known ligand 0.35

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
P2RX4 Q99571 9/20 0.35
MAPT P10636 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
TP53 P04637 1/20 0.32
P2RX1 P51575 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13024025 0.86
SCHEMBL13023330 0.85 P2RX4 (0.42) P2RX4MAPTSMN1; SMN2NPSR1TP53
SCHEMBL13023643 0.84 P2RX4 (0.38) P2RX4MAPTNPSR1
SCHEMBL13023808 0.84 MEN1 (0.33) SMN1; SMN2
SCHEMBL13023709 0.84 P2RX4 (0.35) P2RX4MAPTSMN1; SMN2NPSR1
SCHEMBL13024016 0.81 P2RX4 (0.33) P2RX4MAPTSMN1; SMN2NPSR1TP53
SCHEMBL13022726 0.80 P2RX4 (0.35) P2RX4MAPTSMN1; SMN2NPSR1TP53
SCHEMBL13023834 0.80 MEN1 (0.33) MAPTSMN1; SMN2
SCHEMBL13022526 0.78 P2RX4 (0.41) P2RX4MAPTSMN1; SMN2NPSR1TP53
SCHEMBL13023983 0.75 MAPT (0.38) P2RX4MAPTSMN1; SMN2NPSR1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100286360-A1 POLYMER COMPOUND AND POLYMER LIGHT EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-11-11 US disclosed
US-20100286360-A1 POLYMER COMPOUND AND POLYMER LIGHT EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-11-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100286360-A1 POLYMER COMPOUND AND POLYMER LIGHT EMITTING DEVICE USING THE SAME IGF1R, SCO2, CRY1 P2RX4 4533/4885MAPT 2367/4885SMN1; SMN2 1804/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.