Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | ELANE | P08246 | 2/20 | 0.44 |
| ▸ | MMP2 | P08253 | 4/20 | 0.43 |
| ▸ | MMP3 | P08254 | 4/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.41 |
| ▸ | UBE2N | P61088 | 1/20 | 0.40 |
| ▸ | HRH2 | P25021 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13021628 | 0.96 | POLB (0.53) | POLBHTTKMT2ASMN1; SMN2TDP1 | |
| SCHEMBL28237429 | 0.88 | KMT2A (0.61) | POLBHTTKMT2ASMN1; SMN2TDP1 | |
| SCHEMBL5467762 | 0.86 | POLB (0.53) | POLBHTTKMT2ASMN1; SMN2TDP1 | |
| SCHEMBL9194350 | 0.86 | KMT2A (0.60) | POLBHTTKMT2ASMN1; SMN2TDP1 | |
| SCHEMBL13198393 | 0.84 | MAPT (0.56) | POLBHTTKMT2ASMN1; SMN2TDP1 | |
| SCHEMBL12736709 | 0.83 | POLB (0.48) | POLBHTTKMT2ASMN1; SMN2TDP1 | |
| SCHEMBL7941975 | 0.83 | POLB (0.50) | POLBHTTKMT2ASMN1; SMN2TDP1 | |
| SCHEMBL91806 | 0.83 | POLB (0.50) | POLBHTTKMT2ASMN1; SMN2TDP1 | |
| SCHEMBL13024551 | 0.82 | KMT2A (0.54) | POLBHTTKMT2ASMN1; SMN2TDP1 | |
| SCHEMBL14817247 | 0.82 | KMT2A (0.54) | POLBHTTKMT2ASMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100304148-A1 | Polymerizable liquid crystal compound, polymerizable liquid crystal composition, and polymer thereof | CHISSO CORPORATION | 2010-12-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100304148-A1 | Polymerizable liquid crystal compound, polymerizable liquid crystal composition, and polymer thereof | SSB, CNKSR1, RCC1 | POLB 2115/4885HTT 2665/4885KMT2A 1974/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.