Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.64 |
| ▸ | NPC1 | O15118 | 5/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.64 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.64 |
| ▸ | ABL1 | P00519 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | CLK1 | P49759 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6068055 | 0.86 | RAB9A (0.60) | RAB9ANPC1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL1303393 | 0.86 | RAB9A (0.69) | RAB9ANPC1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL1302984 | 0.85 | ABL1 (0.65) | RAB9ANPC1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL6068064 | 0.85 | RAB9A (0.58) | RAB9ANPC1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL27566826 | 0.83 | RAB9A (0.56) | RAB9ANPC1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL18541791 | 0.81 | LCK (0.62) | RAB9ANPC1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL2792307 | 0.81 | NPC1 (0.78) | RAB9ANPC1DYRK1AABL1GAA | |
| SCHEMBL1783377 | 0.81 | RAB9A (0.74) | RAB9ANPC1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL23900995 | 0.81 | ABL1 (0.66) | RAB9ANPC1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL3860064 | 0.81 | RAB9A (0.57) | RAB9ANPC1CYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119371372-A | Bcr-Abl targeting molecular gel and preparation method and application thereof | 中山大学 | 2025-01-28 | — | — | CN | disclosed |
| CN-119371651-A | Preparation method and application of Bcr-Abl-targeted self-assembled nanomaterial | 中山大学 | 2025-01-28 | — | — | CN | disclosed |
| US-8053574-B2 | Organic compounds | NOVARTIS AG (CH) | 2011-11-08 | — | — | US | disclosed |
| US-8053574-B2 | Organic compounds | NOVARTIS AG (CH) | 2011-11-08 | — | — | US | disclosed |
| US-8053574-B2 | Organic compounds | NOVARTIS AG (CH) | 2011-11-08 | — | — | US | disclosed |
| US-20100197682-A1 | Organic Compounds | NOVARTIS AG | 2010-08-05 | — | — | US | disclosed |
| US-20100197682-A1 | Organic Compounds | NOVARTIS AG | 2010-08-05 | — | — | US | disclosed |
| US-20100197682-A1 | Organic Compounds | NOVARTIS AG | 2010-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100197682-A1 | Organic Compounds | PIK3CA, PI4KA, PI4KB | RAB9A 2332/4885NPC1 1077/4885CYP1A2 3923/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.