⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8776761 | 0.97 | TSHR (0.50) | — | |
| SCHEMBL28955191 | 0.97 | TSHR (0.50) | — | |
| SCHEMBL28605583 | 0.97 | TSHR (0.50) | — | |
| SCHEMBL8668253 | 0.97 | TSHR (0.50) | — | |
| SCHEMBL17707230 | 0.97 | TSHR (0.50) | — | |
| SCHEMBL4653362 | 0.97 | TSHR (0.50) | — | |
| SCHEMBL125167 | 0.92 | — | — | |
| SCHEMBL28191626 | 0.91 | FAAH (0.59) | — | |
| SCHEMBL131915 | 0.80 | — | — | |
| SCHEMBL128509 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107628990-B | Synthesis method of 5-bromopyridine-3-formaldehyde | 南京哈柏医药科技有限公司 | 2021-03-09 | — | — | CN | disclosed |
| US-10190009-B2 | Ink composition, ink jet recording method using same, and colored material | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2019-01-29 | — | — | US | disclosed |
| US-20160160065-A1 | INK COMPOSITION, INK JET RECORDING METHOD USING SAME, AND COLORED MATERIAL | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2016-06-09 | — | — | US | disclosed |
| EP-3015516-A1 | INK COMPOSITION, INK JET RECORDING METHOD USING SAME, AND COLORED MATERIAL | Nippon Kayaku Kabushiki Kaisha (JP) | 2016-05-04 | — | — | EP | disclosed |
| US-8450319-B2 | Pyrrolopyridazinone compound | UBE INDUSTRIES, LTD. (JP) | 2013-05-28 | — | — | US | disclosed |
| EP-1982986-B1 | PYRROLOPYRIDAZINONE COMPOUND AS PDE4 INHIBITOR | UBE INDUSTRIES (JP) | 2012-03-07 | — | — | EP | disclosed |
| CN-1917250-B | Method for making luminous device | UNIV ST ANDREWS | 2010-05-12 | — | — | CN | disclosed |
| CN-100530746-C | Phosphorescent dendrimers for use in light-emitting devices | ISIS INNOVATION UNIV ST ANDREW (GB) | 2009-08-19 | — | — | CN | disclosed |
| CN-101374844-A | Pyrrolopyridazinone compound | UBE INDUSTRIES (JP) | 2009-02-25 | — | — | CN | disclosed |
| US-20090036453-A1 | Pyrrolopyridazinone Compound | UBE INDUSTRIES, LTD. (JP) | 2009-02-05 | — | — | US | disclosed |
| EP-1982986-A1 | PYRROLOPYRIDAZINONE COMPOUND | Ube Industries, Ltd. (JP) | 2008-10-22 | — | — | EP | disclosed |
| CN-1917250-A | Method for making luminous device | ANDREWS UNIVERSITY MAN DEPT (GB) | 2007-02-21 | — | — | CN | disclosed |
| CN-1653857-A | Phosphorescent dendrimers for use in light-emitting devices | ISIS INNOVATION (GB) | 2005-08-10 | — | — | CN | disclosed |
| US-20050143453-A1 | Selective preventing and therapeutic agents for progressive lesion after organic damage | ISHIBASHI MICHIO (JP) | 2005-06-30 | — | — | US | disclosed |
| US-6878745-B2 | Selective preventives/remedies for progressive lesions after organ damage | Ishibashi, Michio (JP) | 2005-04-12 | — | — | US | disclosed |
| US-20030181506-A1 | Selective preventives/remedies for progressive lesions after organ damage | ISHIBASHI, MICHIO (JP) | 2003-09-25 | — | — | US | disclosed |
| EP-1277747-A1 | SELECTIVE PREVENTIVES/REMEDIES FOR PROGRESSIVE LESIONS AFTER ORGAN DAMAGE | Ishibashi, Michio (JP) | 2003-01-22 | — | — | EP | disclosed |