Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.64 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.62 |
| ▸ | MAOB | P27338 | 3/20 | 0.61 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.59 |
| ▸ | BLM | P54132 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.56 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.56 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.55 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.55 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3046006 | 1.00 | ABCG2 (0.64) | ABCG2PTPN1MAOBHDAC8MEN1 | |
| SCHEMBL30066572 | 0.93 | MAOB (0.69) | ABCG2PTPN1MAOBHDAC8MEN1 | |
| SCHEMBL30066569 | 0.93 | MAOB (0.69) | ABCG2PTPN1MAOBHDAC8MEN1 | |
| SCHEMBL27799480 | 0.89 | HDAC8 (0.73) | ABCG2PTPN1MAOBHDAC8MEN1 | |
| SCHEMBL27799479 | 0.89 | HDAC8 (0.73) | ABCG2PTPN1MAOBHDAC8MEN1 | |
| SCHEMBL7751094 | 0.89 | HDAC8 (0.62) | ABCG2PTPN1MAOBHDAC8MEN1 | |
| SCHEMBL7751091 | 0.89 | HDAC8 (0.62) | ABCG2PTPN1MAOBHDAC8MEN1 | |
| SCHEMBL5132842 | 0.88 | MAPT (0.75) | ABCG2PTPN1MAOBHDAC8MEN1 | |
| SCHEMBL2970085 | 0.88 | HDAC8 (0.62) | ABCG2PTPN1MAOBHDAC8MEN1 | |
| SCHEMBL13029333 | 0.88 | HDAC8 (0.62) | ABCG2PTPN1MAOBHDAC8MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2253226-B1 | Use of hydroxyflavone derivatives for modifying taste | LEIBNIZ INST FÜR PFLANZENBIOCHEMIE IPB (DE) | 2015-07-15 | — | — | EP | disclosed |
| EP-2253226-A1 | Use of hydroxyflavone derivatives for modifying taste | Leibniz-Institut für Pflanzenbiochemie (IPB) (DE) | 2010-11-24 | — | — | EP | disclosed |
| US-20100292175-A1 | USE OF HYDROXYFLAVAN DERIVATIVES FOR TASTE MODIFICATION | Leibniz-Institut fur Pflanzenbiochemie (DE) | 2010-11-18 | — | — | US | disclosed |
| US-20100292175-A1 | USE OF HYDROXYFLAVAN DERIVATIVES FOR TASTE MODIFICATION | Leibniz-Institut fur Pflanzenbiochemie (DE) | 2010-11-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100292175-A1 | USE OF HYDROXYFLAVAN DERIVATIVES FOR TASTE MODIFICATION | TAS2R50, TAS2R60, TAS2R30 | ABCG2 432/4885PTPN1 2982/4885MAOB 2412/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.