Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.62 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | MAOB | P27338 | 1/20 | 0.56 |
| ▸ | TNFRSF1A | P19438 | 6/20 | 0.56 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.53 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.53 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13029333 | 1.00 | HDAC8 (0.62) | HDAC8PTPN1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL30066572 | 0.90 | MAOB (0.69) | HDAC8PTPN1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL30066569 | 0.90 | MAOB (0.69) | HDAC8PTPN1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3046006 | 0.88 | ABCG2 (0.64) | HDAC8PTPN1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL13029337 | 0.88 | ABCG2 (0.64) | HDAC8PTPN1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL27799480 | 0.87 | HDAC8 (0.73) | HDAC8PTPN1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL27799479 | 0.87 | HDAC8 (0.73) | HDAC8PTPN1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL5132842 | 0.85 | MAPT (0.75) | HDAC8PTPN1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL25301594 | 0.82 | APP (0.70) | NPC1RAB9AALDH1A1MAPTHPGD | |
| SCHEMBL7751094 | 0.82 | HDAC8 (0.62) | HDAC8PTPN1NPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100292175-A1 | USE OF HYDROXYFLAVAN DERIVATIVES FOR TASTE MODIFICATION | Leibniz-Institut fur Pflanzenbiochemie (DE) | 2010-11-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100292175-A1 | USE OF HYDROXYFLAVAN DERIVATIVES FOR TASTE MODIFICATION | TAS2R50, TAS2R60, TAS2R30 | HDAC8 2183/4885PTPN1 2982/4885NPC1 3006/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.