Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DOT1L | Q8TEK3 | 9/20 | 1.00 |
| ▸ | DNMT1 | P26358 | 7/20 | 1.00 |
| ▸ | DNMT3B | Q9UBC3 | 6/20 | 1.00 |
| ▸ | EZH2 | Q15910 | 4/20 | 1.00 |
| ▸ | CARM1 | Q86X55 | 2/20 | 1.00 |
| ▸ | EHMT2 | Q96KQ7 | 2/20 | 1.00 |
| ▸ | PRMT1 | Q99873 | 2/20 | 1.00 |
| ▸ | NNMT | P40261 | 2/20 | 1.00 |
| ▸ | TRDMT1 | O14717 | 1/20 | 1.00 |
| ▸ | PRMT5 | O14744 | 1/20 | 1.00 |
| ▸ | SUV39H1 | O43463 | 1/20 | 1.00 |
| ▸ | PRMT3 | O60678 | 1/20 | 1.00 |
| ▸ | INMT | O95050 | 1/20 | 1.00 |
| ▸ | NSD2 | O96028 | 1/20 | 1.00 |
| ▸ | PNMT | P11086 | 1/20 | 1.00 |
| ▸ | HNMT | P50135 | 1/20 | 1.00 |
| ▸ | WDR5 | P61964 | 1/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 1/20 | 1.00 |
| ▸ | SETDB1 | Q15047 | 1/20 | 1.00 |
| ▸ | RBBP5 | Q15291 | 1/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| S-Adenosylhomocysteine SCHEMBL804238 | 1.00 | DOT1L (1.00) | DOT1LDNMT1DNMT3BEZH2CARM1 | |
| S-Adenosylhomocysteine SCHEMBL10871157 | 1.00 | DOT1L (1.00) | DOT1LDNMT1DNMT3BEZH2CARM1 | |
| S-Adenosylhomocysteine SCHEMBL17087726 | 1.00 | DOT1L (1.00) | DOT1LDNMT1DNMT3BEZH2CARM1 | |
| S-Adenosylhomocysteine SCHEMBL14434697 | 1.00 | DOT1L (1.00) | DOT1LDNMT1DNMT3BEZH2CARM1 | |
| S-Adenosylhomocysteine SCHEMBL18826562 | 1.00 | DOT1L (1.00) | DOT1LDNMT1DNMT3BEZH2CARM1 | |
| S-Adenosylhomocysteine SCHEMBL17316165 | 1.00 | DOT1L (1.00) | DOT1LDNMT1DNMT3BEZH2CARM1 | |
| S-Adenosylhomocysteine SCHEMBL13073142 | 1.00 | DOT1L (1.00) | DOT1LDNMT1DNMT3BEZH2CARM1 | |
| S-Adenosylhomocysteine SCHEMBL12378912 | 1.00 | DOT1L (1.00) | DOT1LDNMT1DNMT3BEZH2CARM1 | |
| S-Adenosylhomocysteine SCHEMBL21160481 | 1.00 | DOT1L (1.00) | DOT1LDNMT1DNMT3BEZH2CARM1 | |
| S-Adenosylhomocysteine SCHEMBL14411397 | 1.00 | DOT1L (1.00) | DOT1LDNMT1DNMT3BEZH2CARM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160032257-A1 | AGENT AND METHOD FOR MODIFYING THE 5' CAP OF RNA | UNIVERSITAET HAMBURG (DE) | 2016-02-04 | — | — | US | disclosed |
| US-20160032257-A1 | AGENT AND METHOD FOR MODIFYING THE 5' CAP OF RNA | UNIVERSITAET HAMBURG (DE) | 2016-02-04 | — | — | US | disclosed |
| WO-2014090246-A1 | AGENT AND METHOD FOR MODIFYING THE 5' CAP OF RNA | UNIVERSITÄT HAMBURG (DE) | 2014-06-19 | — | — | WO | disclosed |
| US-20100291605-A1 | ASSAYS FOR S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASES | WASHINGTON STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2010-11-18 | — | — | US | disclosed |