Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DOT1L | Q8TEK3 | 9/20 | 1.00 |
| ▸ | DNMT1 | P26358 | 7/20 | 1.00 |
| ▸ | DNMT3B | Q9UBC3 | 6/20 | 1.00 |
| ▸ | EZH2 | Q15910 | 4/20 | 1.00 |
| ▸ | CARM1 | Q86X55 | 2/20 | 1.00 |
| ▸ | EHMT2 | Q96KQ7 | 2/20 | 1.00 |
| ▸ | PRMT1 | Q99873 | 2/20 | 1.00 |
| ▸ | NNMT | P40261 | 2/20 | 1.00 |
| ▸ | TRDMT1 | O14717 | 1/20 | 1.00 |
| ▸ | PRMT5 | O14744 | 1/20 | 1.00 |
| ▸ | SUV39H1 | O43463 | 1/20 | 1.00 |
| ▸ | PRMT3 | O60678 | 1/20 | 1.00 |
| ▸ | INMT | O95050 | 1/20 | 1.00 |
| ▸ | NSD2 | O96028 | 1/20 | 1.00 |
| ▸ | PNMT | P11086 | 1/20 | 1.00 |
| ▸ | HNMT | P50135 | 1/20 | 1.00 |
| ▸ | WDR5 | P61964 | 1/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 1/20 | 1.00 |
| ▸ | SETDB1 | Q15047 | 1/20 | 1.00 |
| ▸ | RBBP5 | Q15291 | 1/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| S-Adenosylhomocysteine SCHEMBL804238 | 1.00 | DOT1L (1.00) | DOT1LDNMT1DNMT3BEZH2CARM1 | |
| S-Adenosylhomocysteine SCHEMBL13033864 | 1.00 | DOT1L (1.00) | DOT1LDNMT1DNMT3BEZH2CARM1 | |
| S-Adenosylhomocysteine SCHEMBL17087726 | 1.00 | DOT1L (1.00) | DOT1LDNMT1DNMT3BEZH2CARM1 | |
| S-Adenosylhomocysteine SCHEMBL14434697 | 1.00 | DOT1L (1.00) | DOT1LDNMT1DNMT3BEZH2CARM1 | |
| S-Adenosylhomocysteine SCHEMBL18826562 | 1.00 | DOT1L (1.00) | DOT1LDNMT1DNMT3BEZH2CARM1 | |
| S-Adenosylhomocysteine SCHEMBL17316165 | 1.00 | DOT1L (1.00) | DOT1LDNMT1DNMT3BEZH2CARM1 | |
| S-Adenosylhomocysteine SCHEMBL13073142 | 1.00 | DOT1L (1.00) | DOT1LDNMT1DNMT3BEZH2CARM1 | |
| S-Adenosylhomocysteine SCHEMBL12378912 | 1.00 | DOT1L (1.00) | DOT1LDNMT1DNMT3BEZH2CARM1 | |
| S-Adenosylhomocysteine SCHEMBL21160481 | 1.00 | DOT1L (1.00) | DOT1LDNMT1DNMT3BEZH2CARM1 | |
| S-Adenosylhomocysteine SCHEMBL14411397 | 1.00 | DOT1L (1.00) | DOT1LDNMT1DNMT3BEZH2CARM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12540946-B2 | Methods and systems for detecting and quantifying large number of molecule biomarkers from a body fluid sample | COMPLETE OMICS INC. (US) | 2026-02-03 | — | — | US | disclosed |
| US-12329726-B2 | Biomarkers for efficacy of prophylactic treatments against stress-induced affective disorders | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2025-06-17 | — | — | US | disclosed |
| US-20240053355-A1 | METHODS AND SYSTEMS FOR DETECTING AND QUANTIFYING LARGE NUMBER OF MOLECULE BIOMARKERS FROM A BODY FLUID SAMPLE | COMPLETE OMICS INTERNATIONAL INC. | 2024-02-15 | — | — | US | disclosed |
| US-20230285322-A1 | Biomarkers for Efficacy of Prophylactic Treatments Against Stress-Induced Affective Disorders | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2023-09-14 | — | — | US | disclosed |
| US-11622948-B2 | Biomarkers for efficacy of prophylactic treatments against stress-induced affective disorders | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2023-04-11 | — | — | US | disclosed |
| US-11427858-B2 | Methods of detecting modified and unmodified DNA | TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED (IL) | 2022-08-30 | — | — | US | disclosed |
| EP-4031681-A1 | LABELLING OF BIOMOLECULES | The University of Birmingham (GB) | 2022-07-27 | — | — | EP | disclosed |
| CN-114712510-A | Application of small molecule inhibitor in preparation of medicine for treating and intervening related diseases through METTL3 | 中国人民解放军空军军医大学 | 2022-07-08 | — | — | CN | disclosed |
| WO-2021053347-A1 | LABELLING OF BIOMOLECULES | THE UNIVERSITY OF BIRMINGHAM (GB) | 2021-03-25 | — | — | WO | disclosed |
| WO-2020225946-A1 | METHOD FOR EVALUATING SAMPLE, ANALYSIS METHOD, METHOD FOR DETECTING DEGRADED SAMPLE, MARKER FOR DETECTING DEGRADED BLOOD PLASMA SAMPLE, AND MARKER FOR DETECTING DEGRADED SERUM SAMPLE | 株式会社島津製作所 | 2020-11-12 | — | — | WO | disclosed |
| US-20200340032-A1 | METHODS OF DETECTING MODIFIED AND UNMODIFIED DNA | TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED (IL) | 2020-10-29 | — | — | US | disclosed |
| US-20200261379-A1 | BIOMARKERS FOR EFFICACY OF PROPHYLACTIC TREATMENTS AGAINST STRESS-INDUCED AFFECTIVE DISORDERS | BPG BIO, INC. | 2020-08-20 | — | — | US | disclosed |
| EP-3662079-A1 | METHODS OF DETECTING MODIFIED AND UNMODIFIED DNA | Technion Research & Development Foundation Limited (IL) | 2020-06-10 | — | — | EP | disclosed |
| WO-2019026075-A9 | METHODS OF DETECTING MODIFIED AND UNMODIFIED DNA | TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED (IL) | 2019-08-29 | — | — | WO | disclosed |
| WO-2019026075-A1 | METHODS OF DETECTING MODIFIED AND UNMODIFIED DNA | TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED (IL) | 2019-02-07 | — | — | WO | disclosed |
| CN-101928749-A | Method for detecting S-adenosylmethionine (AdoMet)-dependent methyltransferase | UNIV JINAN | 2010-12-29 | — | — | CN | disclosed |
| US-4605625-A | RACEMIZATION WITH PSEUDOMONAS | NIPPON ZEON CO., LTD. (JP) | 1986-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12540946-B2 | Methods and systems for detecting and quantifying large number of molecule biomarkers from a body fluid sample | MYADM, EPCAM, CD14 | DOT1L 4173/4885DNMT1 2642/4885DNMT3B 2419/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.