SCHEMBL13034770

SCHEMBL13034770

CC(=O)COCCOCCNC(=O)CC[C@H](NC(=O)CC[C@H](NC(=O)CCCCCNC(=O)CCCS(=O)(=O)NC(=O)CCCCCCCCCCCCCCCc1nnn[nH]1)C(=O)O)C(=O)O

nearest known ligand 0.48

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 8/20 0.48
▸ FOLH1 Q04609 2/20 0.34
▸ CCKAR P32238 8/20 0.34
▸ CCKBR P32239 8/20 0.34
▸ GLO1 Q04760 1/20 0.33
▸ NOD1 Q9Y239 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13034771 1.00 GLP1R (0.48) GLP1RFOLH1CCKARCCKBRGLO1
SCHEMBL16408121 1.00 GLP1R (0.48) GLP1RFOLH1CCKARCCKBRGLO1
SCHEMBL12981346 0.99 GLP1R (0.49) GLP1RFOLH1CCKARCCKBRGLO1
SCHEMBL12122193 0.99 GLP1R (0.46) GLP1RFOLH1CCKARCCKBRGLO1
SCHEMBL16093428 0.98 GLP1R (0.44) GLP1RFOLH1CCKARCCKBRGLO1
SCHEMBL19957501 0.96 GLP1R (0.42) GLP1RCCKARCCKBRNOD1
SCHEMBL19069720 0.96 GLP1R (0.43) GLP1RFOLH1CCKARCCKBR
SCHEMBL14819889 0.94 GLP1R (0.46) GLP1RCCKARCCKBR
SCHEMBL14821762 0.94 GLP1R (0.46) GLP1RCCKARCCKBR
SCHEMBL13034781 0.93 GLP1R (0.43) GLP1RFOLH1CCKARCCKBRGLO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9732137-B2 Semi-recombinant preparation of GLP-1 analogues NOVO NORDISK A/S (DK) 2017-08-15 — — US disclosed
US-20100292133-A1 TRUNCATED GLP-1 DERIVATIES AND THEIR THERAPEUTICAL USE NOVO NORDISK A/S (DK) 2010-11-18 — — US disclosed
US-20100292133-A1 TRUNCATED GLP-1 DERIVATIES AND THEIR THERAPEUTICAL USE NOVO NORDISK A/S (DK) 2010-11-18 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100292133-A1 TRUNCATED GLP-1 DERIVATIES AND THEIR THERAPEUTICAL USE GLP1R, GIPR, IAPP GLP1R 1/4885FOLH1 1672/4885CCKAR 121/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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