SCHEMBL16093428

CC(=O)COCCOCCNC(=O)CC[C@H](NC(=O)CC[C@H](NC(=O)CCCS(=O)(=O)NC(=O)CCCCc1nnn[nH]1)C(=O)O)C(=O)O

nearest known ligand 0.44

Predicted protein targets (top 8)

	gene	UniProt	supporting neighbours	confidence
▸	GLP1R	P43220	8/20	0.44

▸	ITGAV	P06756	1/20	0.33

▸	ITGB6	P18564	1/20	0.33

▸	CCKAR	P32238	6/20	0.33

▸	CCKBR	P32239	6/20	0.33

▸	FOLH1	Q04609	3/20	0.33

▸	GLO1	Q04760	1/20	0.32

▸	NOD1	Q9Y239	1/20	0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL13034771	0.98	GLP1R (0.48)	GLP1RCCKARCCKBRFOLH1GLO1
SCHEMBL12122193	0.98	GLP1R (0.46)	GLP1RITGAVITGB6CCKARCCKBR
SCHEMBL16408121	0.98	GLP1R (0.48)	GLP1RCCKARCCKBRFOLH1GLO1
SCHEMBL13034770	0.98	GLP1R (0.48)	GLP1RCCKARCCKBRFOLH1GLO1
SCHEMBL19069720	0.98	GLP1R (0.43)	GLP1RITGAVITGB6CCKARCCKBR
SCHEMBL12981346	0.96	GLP1R (0.49)	GLP1RCCKARCCKBRFOLH1GLO1
SCHEMBL14819889	0.94	GLP1R (0.46)	GLP1RCCKARCCKBR
SCHEMBL14821762	0.94	GLP1R (0.46)	GLP1RCCKARCCKBR
SCHEMBL19957501	0.93	GLP1R (0.42)	GLP1RITGAVITGB6CCKARCCKBR
SCHEMBL16142393	0.93	GLP1R (0.42)	GLP1RCCKARCCKBRGLO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-8841249-B2	Growth hormones with prolonged in-vivo efficacy	NOVO NORDISK A/S (DK)	2014-09-23	—	—	US	disclosed