SCHEMBL130348

SCHEMBL130348

C1=Cc2ccccc2OC1.[Co].[Ni]

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2B6 P20813 3/20 0.41
STS P08842 1/20 0.40
ABCG2 Q9UNQ0 1/20 0.37
ITGB2 P05107 1/20 0.37
ICAM1 P05362 1/20 0.37
ITGAL P20701 1/20 0.37
CA1 P00915 1/20 0.34
CA9 Q16790 1/20 0.34
LMNA P02545 2/20 0.33
CRHBP P24387 2/20 0.33
CRHR2 Q13324 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
HTT P42858 1/20 0.33
KDM4E B2RXH2 1/20 0.33
MEN1 O00255 1/20 0.33
ALDH1A1 P00352 1/20 0.33
MAPT P10636 1/20 0.33
KMT2A Q03164 1/20 0.33
HTR2C P28335 1/20 0.33
HTR2B P41595 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3434973 0.98 CYP2B6 (0.40) CYP2B6STSABCG2ITGB2ICAM1
SCHEMBL8509034 0.98 CYP2B6 (0.40) CYP2B6STSABCG2ITGB2ICAM1
SCHEMBL28993711 0.98 CYP2B6 (0.40) CYP2B6STSABCG2ITGB2ICAM1
SCHEMBL3406847 0.98 CYP2B6 (0.40) CYP2B6STSABCG2ITGB2ICAM1
SCHEMBL29846230 0.98 CYP2B6 (0.42) CYP2B6STSABCG2ITGB2ICAM1
SCHEMBL29687375 0.98 CYP2B6 (0.42) CYP2B6STSABCG2ITGB2ICAM1
SCHEMBL82421 0.98 CYP2B6 (0.42) CYP2B6STSABCG2ITGB2ICAM1
SCHEMBL28260583 0.98 CYP2B6 (0.42) CYP2B6STSABCG2ITGB2ICAM1
SCHEMBL30285 0.98 CYP2B6 (0.42) CYP2B6STSABCG2ITGB2ICAM1
SCHEMBL1534268 0.96 CYP2B6 (0.39) CYP2B6STSABCG2ITGB2ICAM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 132 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117500458-A Transcatheter Heart Valve (THV) prosthesis system 美利奴生命科学有限公司 2024-02-02 CN claimed
CN-116782857-A Brain support 英特瑞莎血管有限公司 2023-09-19 CN claimed
CN-116747059-A Implantable endoluminal prosthesis 因特雷萨维管股份公司 2023-09-15 CN claimed
CN-115323221-B Cobalt-chromium-nickel alloy, heat treatment process thereof and obtained heat treatment reinforced cobalt-chromium-nickel alloy 三峡大学 2023-08-01 CN claimed
CN-219021752-U Cardiac valve repairing device with flow blocking function 上海傲流医疗科技有限公司 2023-05-16 CN claimed
EP-1408850-B1 DEVICES FOR CAPTURING AND FIXING LEAFLETS IN VALVE REPAIR EVALVE INC (US) 2009-09-23 EP claimed
EP-0932781-B1 HIGH PRESSURE ACTUATED METAL SEATED DIAPHRAGM VALVE PARKER HANNIFIN CORP (US) 2002-01-09 EP claimed
EP-0958479-A4 1999-12-15 EP claimed
EP-0958479-A1 DRY ROLL FURNACE ARRANGEMENT Bricmont, Inc. (US) 1999-11-24 EP claimed
US-5833455-A HEATING FURNACE FOR METALLIC WORKPIECES BRICMONT, INC. (US) 1998-11-10 US claimed
WO-1997043591-A1 DRY ROLL FURNACE ARRANGEMENT BRICMONT, INC. (US) 1997-11-20 WO claimed
JP-7055004-A None JP disclosed
JP-52123315-A None JP disclosed
JP-52143916-A None JP disclosed
JP-52012618-A None JP disclosed
EP-0152754-B1 FOUNDRY MOULDING PROCESS AND MOULD FOR LOW-PRESSURE PRECISION CASTING WITH A GASIFIABLE MODEL AND BINDERLESS SAND MOULD PONT-A-MOUSSON S.A. (FR) 1987-06-16 EP disclosed
EP-0152754-A1 Foundry moulding process and mould for low-pressure precision casting with a gasifiable model and binderless sand mould PONT-A-MOUSSON S.A. (FR) 1985-08-28 EP disclosed
JP-S52143916-A NICKEL CHROME COBALT SUPER HEAT RESISTANT ALLOY EXCELLENT IN HIGH STRENGTH AND OXIDATION RESISTANCE HITACHI METALS LTD 1977-11-30 JP disclosed
JP-S52123315-A ALLOY CONTAINS NICKEL* CHROME* COBALT HUNTINGTON ALLOYS 1977-10-17 JP disclosed
JP-S5212618-A NICKEL CHROME COBALT ALLOY INT NICKEL LTD 1977-01-31 JP disclosed