SCHEMBL30285

SCHEMBL30285

C1=Cc2ccccc2OC1.[Co]

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2B6 P20813 3/20 0.42
STS P08842 1/20 0.41
ABCG2 Q9UNQ0 1/20 0.39
ITGB2 P05107 1/20 0.39
ICAM1 P05362 1/20 0.39
ITGAL P20701 1/20 0.39
CA1 P00915 1/20 0.36
CA9 Q16790 1/20 0.36
LMNA P02545 2/20 0.34
CRHBP P24387 2/20 0.34
CRHR2 Q13324 2/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
HTT P42858 1/20 0.34
KDM4E B2RXH2 1/20 0.34
MEN1 O00255 1/20 0.34
ALDH1A1 P00352 1/20 0.34
MAPT P10636 1/20 0.34
KMT2A Q03164 1/20 0.34
HTR2C P28335 1/20 0.34
HTR2B P41595 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29846230 1.00 CYP2B6 (0.42) CYP2B6STSABCG2ITGB2ICAM1
SCHEMBL1634252 0.98 CYP2B6 (0.41) CYP2B6STSABCG2ITGB2ICAM1
SCHEMBL17835338 0.98 CYP2B6 (0.41) CYP2B6STSABCG2ITGB2ICAM1
SCHEMBL7573755 0.98 CYP2B6 (0.41) CYP2B6STSABCG2ITGB2ICAM1
SCHEMBL10748752 0.98 CYP2B6 (0.41) CYP2B6STSABCG2ITGB2ICAM1
SCHEMBL5670911 0.98 CYP2B6 (0.41) CYP2B6STSABCG2ITGB2ICAM1
SCHEMBL1172584 0.98 CYP2B6 (0.41) CYP2B6STSABCG2ITGB2ICAM1
SCHEMBL130348 0.98 CYP2B6 (0.41) CYP2B6STSABCG2ITGB2ICAM1
Charcoal, Activated SCHEMBL724625 0.98 CYP2B6 (0.41) CYP2B6STSABCG2ITGB2ICAM1
SCHEMBL28941323 0.98 CYP2B6 (0.41) CYP2B6STSABCG2ITGB2ICAM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 17994 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024150237-A1 IMPLANTABLE VENTILATION SYSTEM BREATHIN LTD. (IL) 2024-07-18 WO claimed
EP-4161448-B1 UNICOMPARTIMENTAL KNEE PROSTHESIS GRUPPO BIOIMPIANTI S R L (IT) 2024-07-10 EP claimed
CN-118222951-A Heat treatment method, equipment, cobalt-chromium alloy dental stent and computer storage medium 广东汉邦激光科技有限公司 2024-06-21 CN claimed
WO-2024125806-A1 SYSTEMS FOR OCCLUDING A BLOOD VESSEL CLEARSTREAM TECHNOLOGIES LIMITED (IE) 2024-06-20 WO claimed
US-12011378-B2 Uncaging stent ELIXIR MEDICAL CORPORATION (US) 2024-06-18 US claimed
CN-118203405-A Basket assembly with atraumatic tip electrode and method of making same 伯恩森斯韦伯斯特(以色列)有限责任公司 2024-06-18 CN claimed
US-20240180715-A1 INTERBODY FUSION DEVICES AND RELATED METHODS OF MANUFACTURE MIRUS LLC 2024-06-06 US claimed
US-20240180557-A1 MINIMALLY INVASIVE APPENDECTOMY DEVICE AND METHOD WAKE FOREST UNIVERSITY HEALTH SCIENCES 2024-06-06 US claimed
CN-118121366-A Barbed ball-expanded prosthetic valve prosthesis and transcatheter valve replacement system and method of use 上海傲流医疗科技有限公司 2024-06-04 CN claimed
CN-118121755-A Bone joint prosthesis material and preparation method and application thereof 中国科学院福建物质结构研究所 2024-06-04 CN claimed
EP-0299889-B1 TOTAL SHOULDER PROSTHESIS UNIVERSITE DE BOURGOGNE (U.F.R. DE MEDECINE) (FR) 1992-03-04 EP claimed
WO-1991016009-A1 COATING PROSTHETIC SURFACES WITH MAMMALIAN CELLS CURATIVE TECHNOLOGIES, INC. (US) 1991-10-31 WO claimed
EP-0228399-B1 MIXED DENTAL IMPLANT BOUKHRIS, Gilles (FR) 1991-03-27 EP claimed
EP-0349173-A1 Knee prosthesis Polyzoides, John (GB) 1990-01-03 EP claimed
US-4713077-A Method of applying a chin implant, drill guide tool and implant SMALL IRWIN A (US) 1987-12-15 US claimed
EP-0228399-A1 MIXED DENTAL IMPLANT. BOUKHRIS GILLES (FR) 1987-07-15 EP claimed
WO-1987000030-A1 MIXED DENTAL IMPLANT BOUKHRIS GILLES 1987-01-15 WO claimed
EP-0042271-B1 INTERVERTEBRAL DISC PROSTHESIS Kuntz, David J. (CA) 1984-09-05 EP claimed
US-4349921-A Intervertebral disc prosthesis KUNTZ J DAVID 1982-09-21 US claimed
US-4079469-A Elbow joint endoprosthesis WADSWORTH THOMAS GORDON 1978-03-21 US claimed