Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 1/20 | 0.36 |
| ▸ | PHGDH | O43175 | 1/20 | 0.36 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.35 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.35 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 2/20 | 0.33 |
| ▸ | CNR1 | P21554 | 3/20 | 0.32 |
| ▸ | GUCY1B2 | O75343 | 4/20 | 0.32 |
| ▸ | GUCY1A2 | P33402 | 4/20 | 0.32 |
| ▸ | GUCY1A1 | Q02108 | 4/20 | 0.32 |
| ▸ | GUCY1B1 | Q02153 | 4/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13035109 | 1.00 | PTGER4 (0.36) | PTGER4PHGDHMAPK8MAPK9MAPK10 | |
| SCHEMBL13035070 | 0.93 | PTGER4 (0.36) | PTGER4PHGDHMAPK8MAPK9MAPK10 | |
| SCHEMBL8194184 | 0.91 | PTGER4 (0.37) | PTGER4KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL8199491 | 0.91 | PTGER4 (0.37) | PTGER4KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL13035076 | 0.90 | MAPK8 (0.44) | MAPK8MAPK9MAPK10KDM4EALDH1A1 | |
| SCHEMBL13035388 | 0.87 | GUCY1B2 (0.33) | MAPK8MAPK9MAPK10CNR1GUCY1B2 | |
| SCHEMBL8194380 | 0.84 | GUCY1B2 (0.38) | PTGER4KDM4EHSD17B10CNR1GUCY1B2 | |
| SCHEMBL13035249 | 0.84 | PTGER4 (0.38) | PTGER4KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL8192795 | 0.84 | MAPK8 (0.45) | PTGER4PHGDHMAPK8MAPK9MAPK10 | |
| SCHEMBL13035438 | 0.83 | MAPK8 (0.37) | MAPK8MAPK9MAPK10ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100298314-A1 | NOVEL JNK INHIBITORS | SCHERING CORPORATION | 2010-11-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100298314-A1 | NOVEL JNK INHIBITORS | MAPK1, MAPKAPK2, MAP4K2 | PTGER4 2547/4885PHGDH 2525/4885MAPK8 35/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.