Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.31 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | GRM1 | Q13255 | 5/20 | 0.30 |
| ▸ | F2 | P00734 | 1/20 | 0.30 |
| ▸ | PLG | P00747 | 1/20 | 0.30 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.30 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15692150 | 1.00 | CYP19A1 (0.37) | CYP19A1MEN1KMT2ANPC1ALDH1A1 | |
| SCHEMBL10030798 | 0.95 | CYP19A1 (0.35) | CYP19A1MEN1KMT2ANPC1ALDH1A1 | |
| SCHEMBL18251847 | 0.95 | CYP19A1 (0.35) | CYP19A1MEN1KMT2ANPC1ALDH1A1 | |
| SCHEMBL20276012 | 0.92 | CYP19A1 (0.41) | CYP19A1MEN1KMT2ANPC1ALDH1A1 | |
| SCHEMBL20152476 | 0.92 | CYP19A1 (0.41) | CYP19A1MEN1KMT2ANPC1ALDH1A1 | |
| SCHEMBL20152474 | 0.92 | CYP19A1 (0.41) | CYP19A1MEN1KMT2ANPC1ALDH1A1 | |
| SCHEMBL15588225 | 0.92 | EPHX2 (0.34) | EPHX2MAPK8MAPK10MAPK14ADORA3 | |
| SCHEMBL12377040 | 0.92 | CYP19A1 (0.41) | CYP19A1MEN1KMT2ANPC1ALDH1A1 | |
| SCHEMBL20152479 | 0.92 | CYP19A1 (0.41) | CYP19A1MEN1KMT2ANPC1ALDH1A1 | |
| SCHEMBL20275995 | 0.92 | CYP19A1 (0.41) | CYP19A1MEN1KMT2ANPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7838089-B2 | with biphenylcyclohexane-based skeleton; nematic at room temperature, improved response; paraelectric | SONY CORPORATION (JP) | 2010-11-23 | — | — | US | disclosed |
| US-20090168009-A1 | with biphenylcyclohexane-based skeleton; nematic at room temperature, improved response; paraelectric | SONY CORPORATION (JP) | 2009-07-02 | — | — | US | disclosed |