SCHEMBL13038404

SCHEMBL13038404

CC1(C)CC(NC=O)CC(C)(CN)C1

nearest known ligand 0.38

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.38
ADH1B P00325 4/20 0.34
ADH1A P07327 4/20 0.34
ADH1C P00326 3/20 0.32
ADH7 P40394 2/20 0.32
PBK Q96KB5 1/20 0.32
ADH4 P08319 1/20 0.31
ALDH1A1 P00352 1/20 0.31
CYP3A4 P08684 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16295541 0.83 TSHR (0.39) TSHRPBKALDH1A1CYP3A4
Benzoic Acid SCHEMBL20597405 0.83 PBK (0.37) TSHRPBKALDH1A1CYP3A4
SCHEMBL8750929 0.81 TSHR (0.43) TSHRADH1BADH1AADH1CADH7
SCHEMBL90869 0.81 ADH1B (0.46) TSHRADH1BADH1AADH1CADH7
SCHEMBL1832852 0.78 TSHR (0.38) TSHRPBKALDH1A1CYP3A4
SCHEMBL8499269 0.78 TSHR (0.38) TSHRPBKALDH1A1CYP3A4
SCHEMBL13286287 0.77 ADH1B (0.38) ADH1BADH1AADH1CADH7ADH4
SCHEMBL22212777 0.77 TSHR (0.37) TSHRPBKALDH1A1CYP3A4
SCHEMBL4641340 0.77 TSHR (0.37) TSHRPBKALDH1A1CYP3A4
SCHEMBL21165746 0.76 TSHR (0.52) TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170038499-A1 COMPOSITION FOR MANUFACTURING CONTACT LENSES AND METHOD FOR MANUFACTURING CONTACT LENSES BY USING THE SAME BENQ MATERIALS CORPORATION (TW) 2017-02-09 US disclosed
EP-2267062-A1 Supramolecular polymers containing quadruple hydrogen bonding units in the polymer backbone SupraPolix B.V. (NL) 2010-12-29 EP disclosed